Molecular Characterization of Prolactin in Ovarian Tumors by Radiobinding Assay: Prolactin in Ovarian Tumors

Author:   Hiba Itemad Yousif ,  Sami a Al-Mudhaffar Dr
Publisher:   Createspace Independent Publishing Platform
Volume:   4
ISBN:  

9781511959285


Pages:   270
Publication Date:   11 May 2015
Format:   Paperback
Availability:   Available To Order   Availability explained
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Molecular Characterization of Prolactin in Ovarian Tumors by Radiobinding Assay: Prolactin in Ovarian Tumors


Overview

The developed protocol for the assay of hPRL is suitable for the assessment of PRL in tissues of patients with benign and malignant serous ovarian tumors.A higher incidence of prolactin was obtained in malignant than in benign serous ovarian tumors in tissues and sera.The kinetic studies of 125I-anti hPRL antibody with hPRL in premenopausal and postmenopausal patients with benign and malignant serous ovarian tumors showed that the binding reaction is a temperature and time dependent process. The results indicate that the reaction fits pseude-first order kinetic.The results obtained from the thermodynamics studies on the association of 125I-anti hPRL antibody with hPRL in benign and malignant serous ovarian tumors were spontaneously occurred and the binding reactions were entropically driven.The spectroscopic studies revealed that each of (125I-anti hPRL antibody/PRL) complex and 125I-anti hPRL antibody has a characteristic spectrum.

Full Product Details

Author:   Hiba Itemad Yousif ,  Sami a Al-Mudhaffar Dr
Publisher:   Createspace Independent Publishing Platform
Imprint:   Createspace Independent Publishing Platform
Volume:   4
Dimensions:   Width: 17.00cm , Height: 1.40cm , Length: 24.40cm
Weight:   0.435kg
ISBN:  

9781511959285


ISBN 10:   1511959282
Pages:   270
Publication Date:   11 May 2015
Audience:   General/trade ,  General
Format:   Paperback
Publisher's Status:   Active
Availability:   Available To Order   Availability explained
We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately.

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