Overview

Biomarkers in Cancer Detection and Monitoring of Therapeutics, Volume One, Discovery and Technologies discusses how molecular biomarkers are used to determine predisposition, facilitate detection, improve treatment and offer prevention guidelines for different cancer types. This first volume in the series focuses on techniques and approaches recently developed to assist in the decision of which biomarker to use for specific conditions. Topics covered include circulating tumor cells and circulating tumor DNA, exomes, tumor microenvironment, gene editing, artificial intelligence and robotics. In addition, the book discusses the development and applications of organoids and precision medicine.This book will be a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of biomarkers in cancer research.

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9780323951166

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Professor Sobti is an Education Consultant Governor of Bihar and Senior Scientist at the Indian National Science Academy, in addition to Former Vice Chancellor at Babasaheb Bhimrao Ambedkar University, Lucknow, and Panjab University, Chandigarh, India. Beginning his career as a Cytogeneticist, Professor Sobti moved on to explore the role of gene polymorphisms and their expression in the genesis of various cancers, COPD, AIDS and metabolic syndrome. He has identified disease susceptible / protective novel genotypes and determined the crucial role of SACS-1 and STAT genes in the genesis of cervical and prostate cancers. He has contributed to 270 research publications, 35 books and 23 sponsored research projects. He has received prestigious awards and medals, including the honor of “Padma Shri” from the Government of India for his contribution to higher education. Additionally he was honored with ‘Bharat Gaurav’, Lifetime Achievement Award at the House of Commons, British Parliament, London, UK. Dr. Awtar Krishan PhD is a world-renowned scientist. He obtained his PhD from Panjab University (1962) and the Univ. of Western Ontario, Canada (1963) in Cytogenetics and Anatomy. From 1965 to 1977, he was at the Sidney Farber Cancer Institute, Harvard Medical School as Head of the Tissue Ultrastructure and Experimental Pathology Labs. He has developed flow cytometric techniques for rapid analysis of DNA content by hypotonic propidium iodide, monitoring of drug retention and resistance, and more recently for monitoring hormone receptor expression in archival tumors. He is currently Director, Analytical Cytometry Laboratory, at University of Miami. Aastha Sobti is a Doctoral student at the Department of Immunotechnology at Lund University, Sweden. Her research areas interests include translational medicine, clinical dentistry, cancer immunology, biomarkers, diagnostics and medical oncology.

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