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Author:   Boris Draznin ,  Derek LeRoith
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   Softcover reprint of the original 1st ed. 1994
Dimensions:   Width: 15.20cm , Height: 2.20cm , Length: 22.90cm
Weight:   0.623kg
ISBN:  

9781461266778

ISBN 10:   1461266777
Pages:   404
Publication Date:   27 September 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Molecular Mechanisms of Autoimmunity and Genetics of Diabetes.- 1. Molecular Targets of the Autoimmunity of Type I Diabetes.- 2. Murine Transgenic Models of IDDM.- 3. Pancreatic Islet Transplantation.- 4. Pathogenesis of Autoimmune Diabetes.- Molecular and Cellular Aspects of Insulin Synthesis and Secretion.- 5. Insulin Gene Structure and Regulation.- 6. Molecular Engineering of Glucose-Regulated Insulin Secretion.- 7. Glucokinase Gene Expression and Regulation.- 8. Fundamentals of Fuel Sensing and Intermediary Metabolism in Pancreatic A-and B-Cells.- 9. Glucose Toxicity and the Insulin Gene.- 10. Proinsulin-Processing Endopeptidases.- 11. GTP and Its Binding Proteins in the Regulation of Insulin Exocytosis.- 12. ?-Cell Receptors: Mechanisms of Signal Transduction.- 13. Molecular Biology of the Ion Channels in the Pancreatic ?-Cell.- 14. Molecular Biology of Gap Junction Proteins.- 15. The Gluco-Incretin Hormone Glucagon-Like Peptide-1 and Its ?-Cell Receptor.- 16. Islet Amyloid Polypeptide (IAPP) and Insulin Secretion.

Reviews

This is an essential book for a medical library to have, and it is a welcome addition to the library of investigators in the field. Specialists in diabetes will also find this book very useful. - Kevan Herold, MD for Doody's Health Science Book Review Journal

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