Overview
This readily comprehensible book explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. With its examination of these novel methods and generous practical advice, this is essential reading for all pharmaceutical chemists, molecular biologists and medical researchers using molecular methods to study drugs and their action.
Full Product Details
Author: Theodor Dingermann (University of Frankfurt, Germany) ,
Dieter Steinhilber (University of Frankfurt, Germany) ,
Gerd Folkers (ETH Zürich, Switzerland) ,
Raimund Mannhold (University of Düsseldorf, Ge)
Publisher: Wiley-VCH Verlag GmbH
Imprint: Blackwell Verlag GmbH
Dimensions:
Width: 17.80cm
, Height: 2.50cm
, Length: 24.60cm
Weight: 0.984kg
ISBN: 9783527304318
ISBN 10: 3527304312
Pages: 435
Publication Date: 29 January 2004
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Hardback
Publisher's Status: Active
Availability: Awaiting stock
The supplier is currently out of stock of this item. It will be ordered for you and placed on backorder. Once it does come back in stock, we will ship it out for you.
Reviews
...a book that should definitely be on the shelves of a modern practitioner of medicinal chemistry... (Journal of Natural Products, February 2005) ...a welcome addition to the library of anyone seeking to build a multidisciplinary group (Applied Organometallic Chemistry, June 2004) In all, the book touches on some of the trendiest subjects that interface to form the frontier of modern medicinal chemistry. (Kevin G. Rice, Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, Iowa City, Journal of Medicinal Chemistry, Vol. 47, No. 26, 2004)
...a welcome addition to the library of anyone seeking to build a multidisciplinary group Applied Organometallic Chemistry, June 2004 In all, the book touches on some of the trendiest subjects that interface to form the frontier of modern medicinal chemistry. Kevin G. Rice, Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, Iowa City, Journal of Medicinal Chemistry, Vol. 47, No. 26, 2004
...a welcome addition to the library of anyone seeking to build a multidisciplinary group Applied Organometallic Chemistry, June 2004 In all, the book touches on some of the trendiest subjects that interface to form the frontier of modern medicinal chemistry. Kevin G. Rice, Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, Iowa City, Journal of Medicinal Chemistry, Vol. 47, No. 26, 2004 Molecular Biology in Medicinal Chemistry ist eine exzellente EinfA1/4hrung in einige wichtige Aspekte der pharmazeutischen Forschung und der Chemischen Biologie. Jeder Wissenschaftler, der sich fA1/4r diese Gebiete interessiert, sollte A1/4ber seine Bibliothek Zugriff auf dieses Buch haben. Rolf Breinbauer Angewandte Chemie It is not the book screening for beginners but, thanks to the wide range of topics, every reader will find several very interesting chapters in it. The readership is addressed in the title: medicinal chemists in industry and academia. I, for my part, found far more in it than I expected. Boris Schmidt ChemBioChem 8/2004 Das von Dingermann, Steinhilber und Folkers zusammengestellte Autorenteam beleuchtet in kompetenter und aufschluA reicher Weise den gegenwArtigen Stand und Stellenwert der molekularebiologischer Methoden und Techniken im Bereich der pharmazeutischen Chemie. ... Mit dem Themenblock Kinetik, Metabolismus und Toxikologie schlieA t das Buch ab. Diese hervorragende Zusammenstellung A1/4ber den aktuellen Stand von Pharmacogenomics und Toxicogenomics sowie die umfassende und detaillierte Referenzliste setzt MaA stAbe und wAre allein schon Grund genug das Buch zu erwerben. Stefan MA1/4ller, KAln, Arzneimittel-Forschung/Drug Research, 1/05
Author Information
Theodor Dingermann, born 1948, studied pharmacy at the University of Erlangen, Germany. After obtaining his PhD in biochemistry, he worked as a post-doc at Yale University, New Haven. In 1987 he completed his habilitation for the disciplines of biochemistry and molecular biology. Since 1990 he is full professor of pharmaceutical biology at Goethe University in Frankfurt, Germany. He is editor-in-chief of two journals, ""Die Pharmazie"" and ""Pharmazie in unserer Zeit"". Furthermore, he is chairman of the working group on biopharmaceuticals and vice-chairman of the committee on pharmaceutical biology of the German Arzneibuch commission. From 2000 to 2004 he has been President of the German Pharmaceutical Society. Dieter Steinhilber, born 1959, studied pharmacy at the University of Tubingen (Germany). After an assistantship there he spent a postdoc period with Nobel prize winner Bengt Samuelsson in Stockholm (Sweden). In 1994 he received an associate professorship and since 2000 he is a full professor for pharmaceutical chemistry at the Goethe University in Frankfurt (Germany). He is also the chairman of the scientific advisory board of Phenion, a company for molecular cell physiology. Gerd Folkers is professor of pharmaceutical chemistry at the ETH Zurich since 1991. He studied pharmacy at the University of Bonn and earned his Ph.D. on structure-activity relationships of desapurines. He then moved to the University of Tubingen, where he completed his habilitation in pharmaceutical chemistry. During a stay with H.-D. Hoeltje in Bern, he studied new research methods in computer-aided molecular design and expanded this knowledge during other stays with T. Blundell at the Birkbeck College and E. Meyer at Texas A&M University. The focus of his research is the molecular interaction between drugs and their binding sites. Besides his work on the molecular mechanism of ""conventional"" nucleoside therapeutics against virus infections and cancer, his special interest has shifted to immuno-therapeutics.
