Overview

Molecular and Genetic Analysis of Human Traits is the first concise presentation of what is unique about human genetics. Designed to introduce human genetics to undergraduate and graduate students who are familiar with basic genetics, the text assumes knowledge of meiosis and Mendelian genetics as well as the basic principles of transmission of information from DNA to RNA to proteins. Professor Maroni's engaging presentation is both authoritative and student-oriented. Outstanding features highlight this groundbreaking first edition: Incorporates two basic themes throughout: ""How do we establish that a trait is hereditary?"" and ""How can the properties of a trait be explained by the underlying molecular causes?"" Compares standard genetic approaches to those needed for studying inheritance in humans Prepares students for understanding the original literature by clear presentation of actual experiments Chapters 3 and 4 include thorough treatment of the human genome project as explained in its rationale, its development, and its conclusion Provides a comprehensive explanation of how genes are mapped by describing the four methods most commonly used: linkage analysis, affected pedigree member, allelic association, and candidate gene Exceptional student-friendly pedagogy: Describes a wealth of applications, including: how genetics is used in understanding cancer (Chapter 8) and how genetic predictions impact counseling for families who are at risk (Chapter 9) Addresses relevant clinical examples and key related ethical issues The Human Genome Project Box includes the latest, culminating research Internet Site Boxes refer to pertinent human genetics URLs Chapter opening contents, margin notes, two-color figures, four-color insert, examples, conclusions, end-of-chapter exercises, over 150 original literature citation, and much more!

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9780632043699

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Reviews

"I will be looking for a new general text that does a good job presenting the basics - the clinical texts will not do that for me, nor will the texts that present human genetics as problems to be solved, one disease at a time. I would be interested in considering this text should it be published." Joan Rutila, Brandeis University "I DO agree with the author's two lines of thought, I think they are very good approaches and in texts that I have reviewed, I have not found such an organisation. If I were teaching a majors course with a lecture format, I would like such an approach." Rita Calvo, Cornell University Praise from reviews: The author has clearly done a great deal of research across a broad spectrum of genetic studies in finding the examples that he has chosen to illustrate concepts. I would like to adopt this text for my class, and I think it will help students learn how to read original research publications. - Professor Georgia Floyd Smith, Arizona State University The coverage of ethics, particularly the box regarding the human genome project, is excellent. These are the types of side-trips that make teaching fun. A text which relates "issues" to the material makes the material relevant for students while giving the instructor an opportunity to lead an interesting discussion. - Professor Ellen Kittler, UMass Medical School

I will be looking for a new general text that does a good job presenting the basics - the clinical texts will not do that for me, nor will the texts that present human genetics as problems to be solved, one disease at a time. I would be interested in considering this text should it be published. Joan Rutila, Brandeis University I DO agree with the author's two lines of thought, I think they are very good approaches and in texts that I have reviewed, I have not found such an organisation. If I were teaching a majors course with a lecture format, I would like such an approach. Rita Calvo, Cornell University Praise from reviews: The author has clearly done a great deal of research across a broad spectrum of genetic studies in finding the examples that he has chosen to illustrate concepts. I would like to adopt this text for my class, and I think it will help students learn how to read original research publications. - Professor Georgia Floyd Smith, Arizona State University The coverage of ethics, particularly the box regarding the human genome project, is excellent. These are the types of side-trips that make teaching fun. A text which relates issues to the material makes the material relevant for students while giving the instructor an opportunity to lead an interesting discussion. - Professor Ellen Kittler, UMass Medical School

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