Overview

This collection of cutting-edge reviews of the molecular and cellular bases of inflammatory processes makes an important and timely contribution to the search for new antiinflammatory agents. The book authoritatively reviews the role of protein and lipid mediators in inflammation, cellular processes of importance in the initiation and determination of inflammation, signal transduction events of interest in the development of potential new therapeutic targets, and drug design issues in inflammation therapeutics. In addition, several chapters summarize state-of-the-art findings in disease processes where inflammation plays a critical role. Reflecting the work of leading researchers in molecular biology, biochemistry, pharmacology, immunology, and pathobiology, Molecular and Cellular Basis of Inflammation establishes new basic concepts in the elucidation of molecular mechanisms in inflammation.

Full Product Details

Author:   Charles N. Serhan ,  Peter A. Ward
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   1999 ed.
Dimensions:   Width: 17.80cm , Height: 2.30cm , Length: 25.40cm
Weight:   0.948kg
ISBN:  

9780896035959

ISBN 10:   0896035956
Pages:   338
Publication Date:   09 December 1998
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

Ch. 1. Role of Complement in Endothelial Cell Activation.- Ch. 2. Angiogenesis.- Ch. 3. Update on Arachidonic Acid Cascade: Leukotrienes and Lipoxins in Disease Models.- Ch. 4. Mutagenesis Studies of Mammalian Lipoxygenases.- Ch. 5. Lipid-Mediator-Deficient Mice in Models of Inflammation.- Ch. 6. Isoprostanes in the Assessment of Oxidant Stress In Vivo.- Ch. 7. Isoprostanes as Markers of Lipid Peroxidation in Atherosclerosis.- Ch. 8. Structure and Regulation of NADPH Oxidase of Phagocytic Leukocytes: Insights from Chronic Granulomatous Disease.- Ch. 9. Recruitment of ?/? T-Cells and Other T-Cell Subsets to Sites of Inflammation.- Ch. 10. The N-Formyl Peptide Receptor: Structure, Signaling, and Disease.- Ch. 11. Pathobiology of Neutrophil Interactions with Polarized Columnar Epithelia.- Ch. 12. Adenosine and Its Receptors During Inflammation.- Ch. 13. Quantitative Studies of the Lipid Mediators of Inflammation Using Liquid Chromatography-Electrospray Mass Spectrometry.- Ch. 14. Molecular Biology of Autoimmune Arthritis.- Ch. 15. Lupus Erythematosus: The Role of Adhesion Molecules and Local Mediators.

Reviews

...this book provides a comprehensive description of our current knowledge of inflammation. It contains some useful figures and tables that provide the reader with a very good overview of the knowledge ... an important read for scientists and clinicians who are interested in inflammation. - FEBS Letters a book which changes the views of the inflammation! - Cellular and Molecular Biology

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