Overview

The leading reference on the topic, written by first-class authors from leading companies. Three topical volumes cover herbicides, fungidcides, and insecticides in terms of chemistry, mode of action, commercial use and industrial synthesis.

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Author:   Wolfgang Kr¿mer ,  Ulrich Schirmer ,  Peter Jeschke ,  Matthias Witschel
Publisher:   Wiley-VCH Verlag GmbH
Imprint:   Wiley-VCH Verlag GmbH
Edition:   2nd, Revised and Enlarged Edition, 3 Volume Set
Dimensions:   Width: 17.30cm , Height: 8.40cm , Length: 24.40cm
Weight:   3.530kg
ISBN:  

9783527329656

ISBN 10:   352732965
Pages:   1608
Publication Date:   14 December 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

VOLUME 1: HERBICIDES Overview HRAC CLASSIFICATION OF HERBICIDES AND RESISTANCE DEVELOPMENT Introduction HRAC Classification System of Herbicides Herbicide Resistance ACETOHYDROXYACID SYNTHASE INHIBITORS (AHAS/ALS) Biochemistry of the Target and Resistance Newer Sulfonylureas Imidazolinone Herbicides Triazolopyrimidines Pyrimidinylcarboxylates and Sulfonanilides Sulfonylaminocarbonyl-Triazolinones PROTOPORPHYRINOGEN IX OXIDASE INHIBITORS Introduction Historical Development Non-Classical Protox Chemistries Recent Developments Toxicology Summary HERBICIDES WITH BLEACHING PROPERTIES Phytoene Desaturase Inhibitors Hydroxyphenylpyruvate Dioxygenase (HPPD): The Herbicide Target Triketones Hydroxyphenylpyruvate Dioxygenase (HPPD) Inhibitors: Heterocycles NEW AUXIN MIMICS AND HERBICIDES The Molecular Mode of Action of Auxin Herbicides Aminopyralid Pyrimidine Carboxylic Acids, Aminocyclopyrachlor HERBICIDES DISTURBING THE SYNTHESIS OF VERY LONG-CHAIN FATTY ACIDS (VLCFAs) Inhibitors of the Synthesis of Very Long-Chain Fatty Acids (VLCFAs) Chemistry and Biology of Oxyacetamides, Tetrazolinones, and Triazolinones Isoxazolines INHIBITORS OF CELLULOSE BIOSYNTHESIS Introduction Cellulose Biosynthesis Inhibitors from Different Chemical Substance Classes Cellulose Biosynthesis Inhibitors from Natural Sources SAFENERS FOR HERBICIDES Introduction Overview of Selected Safeners Mechanisms of Herbicide Safener Action Mode of Action of Safeners in Agricultural Practice Concluding Remarks GENETICALLY MODIFIED HERBICIDE-RESISTANCE CROPS Overview Inhibitors of 5-Enolpyruvyl Shikimate 3-Phosphate Synthase (EPSPS) Glutamine Synthetase Inhibitors MICROTUBULIN ASSEMBLY INHIBITORS (PYRIDINES) Introduction Biology of the Microtubulin Assembly Inhibitors (Pyridines) Environmental Fate of Microtubulin Assembly Inhibitors (Pyridines) Toxicology of Microtubulin Assembly Inhibitors (Pyridines) Mode of Action of Microtubulin Assembly Inhibitors (Pyridines) Synthesis of Dithiopyr and Thiazopyr ACETYL-CoA CARBOXYLASE INHIBITORS Introduction Biochemistry Chemistry of ACCase Inhibitors Structure-Activity Relationships Pinoxaden Summary and Outlook PHOTOSYNTHESIS INHIBITORS: REGULATORY ASPECTS, RE-REGISTRATION IN EUROPE, MARKET TRENDS, AND NEW PRODUCTS Introduction The Re-Registration in the European Union Main Changes in Guidelines Regarding EU RE-Registration New Regulations in Europe Situation of PS II Inhibitors in the EC Markets Current Market Share of PS II Compound Groups A New Herbicide for Corn and Sugarcane: Amicarbazone - BAY MKH Conclusions NEW ASPECTS OF PLANT REGULATIONS Introduction Plant Growth Regulators PGRs in Modern Agriculture Conclusions and Developments VOLUME 2: FUNGICIDES Overview FRAC MODE OF ACTION CLASSIFICATION AND RESISTANCE RISK OF FUNGICIDES History of Fungicide Use Fungicides: Importance of Individual Modes of Action Fungicide Resistance Fungicides Classes and Modes of Action FUNGICIDES ACTING ON OXIDATIVE PHOSPHORYLATION The Biochemistry of Oxidative Phosphorylation: A Multiplicity of Targets for Crop Protection Chemistry Strobilurins and Other Complex III Inhibitors Succinate Dehydrogenase Inhibitors Uncouplers of Oxidative Phosphorylation NADH Inhibitors (Complex I) FUNGICIDES ACTING ON AMINO ACIDS AND PROTEIN SYNTHESIS Natural Compounds Used in Agriculture Interfering in Protein Synthesis of Fungi and Bacteria Anilinopyrimidines: Methionine Biosynthesis Inhibitors FUNGICIDES ACTING ON SIGNAL TRANSDUCTION Mode of Action Chemistry and Biology of Fludioxonil, Fenpiclonil, and Quinoxyfen FUNGICIDES ACTING ON MITOSIS AND CELL DIVISION Zoxamide: An Antitubulin Fungicide for the Control of Oomycete Pathogens Pencycuron: A Phenylurea Fungicide for Rhizoctonia solani STEROL BIOSYNTHESIS INHIBITORS Sterol Biosynthesis Inhibitor SBI Fungicides in Agriculture SBI Class I: DMI Fungicides SBI Class II: Amines SBI Class III: Hydroxyanilides SBI Class IV: Squalene Epoxidase Inhibitors CARBOXYLIC ACID AMIDE (CAA) FUNGICIDES Introduction Chemistry of the Carboxylic Acid Amides Biological Activity of Carboxylic Acid Amides Mode of Action and Mechanism of Resistance of the CAA Fungicides FLUOPICOLIDE: A NEW ANTI-OOMYCETES FUNGICIDE? Introduction Chemical and Physical Properties Toxicology/Ecotoxicology Spectrum of Activity Effect of Fluopicolide on Spectrin-Like Protein Distribution Conclusion MELANIN SYNTHESIS IN THE CELL WALL Biological Occurrence and Function of Melanin in Fungi Overview: Fungicides Inhibiting DHN Melanin Biosynthesis Biology of Scytalone Dehydratase Inhibitors Biochemical Reaction Mechanim of Scytalone Dehydratase and Structure-Based Inhibitor Design Chemistry and Stereochemistry of Carpropamid Resistance Problems and Successful Management in Japan Final Remarks FUNGICIDES WITH UNKNOWN MODE OF ACTION Introduction Cymoxanil Fosetyl-Aluminum Flusulfamide Diclomezine Triazoxide Tebufloquin RECENTLY INTRODUCED POWDERY MILDEW FUNGICIDES Introduction Cyflufenamid Metrafenone Pyriofenone Proquinazid Flutianil Conclusions NEWEST ASPECTS OF NUCLEIC ACID SYNTHESIS INHIBITORS: METALAXYL-M Introduction Chemistry of Metalaxyl-M/Mefenoxam Biological Activity Mode of Action and Mechanism of Resistance Degradation and Metabolism of the Two Enantiomers HOST DEFENSE INDUCERS Introduction General Mechanism of Induced Resistance Market Products Summary and Outlook VOLUME 3: INSECTICIDES Overview IRAC: Insecticide Resistance, and Mode of Action Classification of Insecticides Introduction Objectives of the IRAC Structure and Organization of the IRAC Activities Principles of Resistance The Mode of Action (MoA) Classification Scheme v7.0, August 2010 Effective IRM Strategies and Approved Principles Future Market Trends Conclusions INSECT MOLTING AND METAMORPHOSIS Bisacylhydrazines: Novel Chemistry for Insect Control Pyriproxyfen: A New Juvenoid CHITIN SYNTHESIS Chitin Synthesis and Inhibitors Mite Growth Inhibitors: Clofentezine, Hexythiazox, Etoxazole MIDGUT - TRANSGENIC CROPS EXPRESSING Bacillus thuringiensis CRY PROTEINS Introduction Plant Engineering Insecticidal Crystal Proteins from B. thuringiensis Bt Plants Insect Resistance to Bt Resistance Management with Bt Plants Safety of Bt Plants Conclusions METABOLIC PROCESSES Inhibitors of Oxidative Phosphorylation Inhibitors of Oxidative Phosphorylation via Disruption of the Proton Gradient Inhibitors of Mitochondrial Electron Transport: Acaricides and Insecticides Inhibitors of Lipid Synthesis: Acetyl-CoA-Carboxylase Inhibitors NERVOUS SYSTEM Nicotinic Acetylcholine Receptor Agonists: Target and Selectivity Aspects Chemical Structural Features of Commercialized Neonicotinoids Sulfoxaflor Spinosad and Spinetoram, a New Semi-Synthetic Spinosyn Sodium Channel-Blocking Insecticides Ligand-Gated Chloride Channel Antatgonists (Fiproles) Chloride Channel Activators/New Natural Products: Avermectins and Milbemycins NEW UNKNOWN MODES OF ACTION Selective Feeding Blockers: Pymetrozine, Flonicamid, and Pyrifluquinazon Acaricides with Undefined Mode of Action: Bifenazate, Cyflumetofen, and Amidoflumet Pyridalyl: Discovery, Insecticidal Activity, and Mode of Action Recent Nematicides INSECTICIDES AFFECTING CALCIUM HOMEOSTASIS Ryanodine Receptor Modulators: Diamides Flubendiamide Anthranilic Diamide Insecticides: Chlorantraniliprole and Cyantraniliprole Index of Common Names Subject Index

Reviews

Modern crop protection compounds is a comprehensive source of accumulated information about modern agrochemicals and the research that led to their use in agriculture. (Chemistry & Industry, 1 October 2012)

Modern crop protection compounds is a comprehensive source of accumulated information about modern agrochemicals and the research that led to their use in agriculture. ( Chemistry & Industry , 1 October 2012)

<p> Modern crop protection compounds is a comprehensivesource of accumulated information about modern agrochemicals andthe research that led to their use in agriculture. (Chemistry & Industry, 1 October 2012)

Author Information

Wolfgang Krämer gained his PhD in organic chemistry from the TU Stuttgart (Germany) in 1968, after which he joined the Institute of Textile Chemistry at Stuttgart University, bevore moving to Bayer Plant Protection as lab leader in plant protection research in 1970. Between 1984 and 1990 he was Head of Global Chemistry Fungicides, and Head of Insecticide Chemistry thereafter.Retired since 2005, Dr. Krämer has over 250 patent applications and publications to his name. Ulrich Schirmer received his PhD in organic chemistry from Stuttgart University (Germany) in 1973, and subsequently carried out his postdoc at Paris-Orsay (France). He joined BASF in 1974, eventually becoming Senior Vice President responsible for plant protection research for chemical synthesis, process development and biological R&D. Since 2003, he has been working as a freelance consultant to start-ups in the fields of biotechnology, chemistry and agriculture. Dr. Schirmer is author and co-author of more than 100 patent applications and scientific publications. Peter Jeschke gained his PhD in organic chemistry at the University of Halle/Wittenberg (Germany), after which he moved to Fahlberg-List Company (Germany) to pursue agrochemical research before going to the Institute of Neurobiology and Brain Research, German Academy of Sciences. In 1989 je joined Bayer as lab leader in animal health research and eight years later he took a position at the Bayer Crop Protection Business Group, where he is currently Head of Research Pest Control Chemistry 2. Since 2011, he is honorary professor at the University of Düsseldorf (Germany). Prof. Dr. Jeschke has more than 180 patent applications and scientific publications to his name. Matthias Witschel received his PhD in organic chemistry in 1994 at the University of Erlangen-Nürnberg (Germany). After his post-doctoral stay at Stanford University, California (USA), he started in 1996 at BASF in herbicide research, where he is now Principal Scientist in the Global Research Herbicides, Agricultural Products, based in Ludwigshafen (Germany). Dr. Witschel is the author and co-author of over 160 patents and scientific publications.

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