Overview

With the current volume of the Karger book series Contributions to Microbiology, we attempt to provide an overview of models of exacerbations of asthma and chronic obstructive pulmonary disease. This is a large area so within one volume we cannot be totally comprehensive. However, we have attempted to point to experimental systems that mimic the pathobiological processes likely to be critical in the exacerbations of these conditions. By the same token we asked the contributors to describe both animal models and human experimental models, since we believe that knowledge generated by linking both these systems will be required to generate insight into the mechanisms of exacerbations of pulmonary disease and the discovery of future treatments. For this update, we were very honored to have been able to recruit some of the most eminent scientists within the area of pulmonology to give their insights into this evolving field of human medicine. We hope that this volume will serve to stimulate and provoke thoughts in a research area where much work remains to be done to meet the high unmet medical needs.

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9781280940965

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