Mitochondria and Cancer
Author:   Keshav Singh ,  Leslie Costello
Publisher:   Springer-Verlag New York Inc.
Edition:   2009 ed.
ISBN:  

9780387848341


Pages:   289
Publication Date:   12 December 2008
Format:   Hardback
Availability:   In Print   Availability explained
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

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Mitochondria and Cancer


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Overview

The book begins with a general overview of Warburg Hypothesis, mitochondrial structure and function, and then outline more specifically the metabolic and molecular alterations in mitochondria that are associated with human cancer and their clinical implications. An emphasis is also placed on mtDNA mutations and their potential role in carcinogenesis. The potential use of mitochondria as biomarkers for early detection of cancer, or as unique cellular targets for novel and selective anti-cancer agents will also be discussed.

Full Product Details

Author:   Keshav Singh ,  Leslie Costello
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2009 ed.
Dimensions:   Width: 15.50cm , Height: 1.80cm , Length: 23.50cm
Weight:   0.567kg
ISBN:  

9780387848341


ISBN 10:   0387848347
Pages:   289
Publication Date:   12 December 2008
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   In Print   Availability explained
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

Table of Contents

Mitochondria and Cancer.- Warburg and his Legacy.- The Lipogenic Switch in Cancer.- Citrate Metabolism in Prostate and Other Cancers.- Integration of Genetic, Proteomic, and Metabolic Approaches in Tumor Cell Metabolism.- Mitochondrial Respiration and Differentiation.- Integration of Energy Metabolism and Control of Apoptosis in Tumor Cells.- Energy Generating Pathways and the Tumor Suppressor p53.- Mitochondrial Tumor Suppressors.- Mitochondria in Hematology.- Mitochondria and Oncocytomas.- Mitochondria as Targets for Cancer Therapy.- Reversing the Warburg Effect: Metabolic Modulation as a Novel Cancer Therapy.- Mitochondrial Nanotechnology for Cancer Therapy.

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