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OverviewOne of the most promising new approaches for the prevention of HIV transmission, particularly for developing countries, involves topical, self-administered products known as microbicides. The development of microbicides is a long and complicated process, and this volume provides an overview of all the critical areas, from the selection of appropriate candidate molecules and their formulation, preclinical and clinical testing for safety and efficacy, strategies for product registration and finally, issues associated with product launch, distribution and access. The book will prove valuable to both those working in the field and all others who are interested in learning more about this product class, which has the potential to significantly impact the future of this devastating epidemic. Full Product DetailsAuthor: Jeremy NuttallPublisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K Edition: Softcover reprint of the original 1st ed. 2014 Volume: 383 Dimensions: Width: 15.50cm , Height: 1.00cm , Length: 23.50cm Weight: 2.993kg ISBN: 9783662522615ISBN 10: 3662522616 Pages: 179 Publication Date: 23 August 2016 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand ![]() We will order this item for you from a manufactured on demand supplier. Table of ContentsCandidate Microbicides and Their Mechanisms of Action Carolina Herrera and Robin J. Shattock Microbicide Dosage Forms L.C. Rohan, B. Devlin and H. Yang Preclinical Safety Evaluation Jonathon D. S. Holt and Jeremy P. Nuttall Clinical Safety and Pharmacology Trial Christine Mauck, Andrea Thurman and Jill Schwartz Microbicides for Prevention of HIV Infection: Clinical Efficacy Trials Salim S. Abdool Karim and Cheryl Baxter Rectal Microbicide Development Ian McGowan and Charlene Dezzutti Developing Regulatory Strategy for Microbicides Ronald Nardi, Linda Arterburn, and Lisa Carlton Preparing for Microbicide Introduction, Rollout and Sustained Access Cynthia Woodsong, Tim Farley and Elizabeth McGroryReviews""This book offers a detailed review of essentially all aspects of microbicide development, from the basic science underlying microbicide action, to strategic considerations when implementing international microbicide programs. ... This text could be used as a primer for researchers entering the burgeoning field of microbicide development or for clinicians who provide these agents."" (Douglas S. Krakower, Clinical Infectious Diseases CID, Vol. 60, June, 2015) This book offers a detailed review of essentially all aspects of microbicide development, from the basic science underlying microbicide action, to strategic considerations when implementing international microbicide programs. ... This text could be used as a primer for researchers entering the burgeoning field of microbicide development or for clinicians who provide these agents. (Douglas S. Krakower, Clinical Infectious Diseases CID, Vol. 60, June, 2015) Author InformationTab Content 6Author Website:Countries AvailableAll regions |