Overview

The book starts with dissecting mechanisms underlying viral immune evasion via exploiting the host complement system by vaccinia virus, and by modulating the type 1 interferon response by RNA viruses. Yet another chapter looks into how viroporins expressed by different families of viruses causing influenza A virus, SARS, hepatitis C and HIV interact with several cellular pathways. Understanding of these mechanisms can aid the development of novel potential anti‑viral targets. The chapter on tuberculosis discusses the emerging importance of the innate immune mechanisms against Mycobacterium tuberculosis infection and latency. This book has a strong focus on fungal pathogenesis and immunity, starting with virulence and host factors that attain great importance in candidiasis and associated escape tricks of seriously opportunistic fungi. Two chapters on Aspergillus fumigatus elaborate on the pathogenic mechanisms: first discussing A. fumigatus‑airway epithelium interaction, followed by fungal and host factors that are paramount in the development of allergic and invasive aspergillosis. In the subsequent chapter, there is a general discussion on the innate and adaptive immune responses against primary and opportunistic fungal pathogens.

Full Product Details

Author:   Uday Kishore ,  Annapurna Nayak
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2014 ed.
Volume:   798
Dimensions:   Width: 17.80cm , Height: 2.30cm , Length: 25.40cm
Weight:   0.658kg
ISBN:  

9781461495291

ISBN 10:   1461495296
Pages:   305
Publication Date:   04 December 2013
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

The Complement System as a Viral Target for Immune Evasion.-  Modulation of Type I Interferon Response by RNA Viruses.- Viroporins: Differential Functions at Late Stages of Viral Life Cycles.- Mycobacterium tuberculosis: Innate Immune Recognition and Persistence.- Candida and Candidiasis.- Mechanisms of Pathogenesis of Aspergillosis.- Airway Epithelium Interactions with Aspergillus fumigatus.- Anti‑Fungal Innate and Adaptive Immune Responses.- Host‑pathogen interaction in Malaria and Trypa nosomiasis.- The Host Pathogen Interaction and Immunomodulation During Leishmaniasis.- Immune responses induced by parasitic worms.- Pathogenic Persistence and Evasion mechanisms in Schistosomiasis.- Transmissible Spongiform Encephalopathies: Passage from Gut to Brain.

Reviews

Author Information

Uday Kishore Annapurna Nayak Centre for Infection, Immunity and Disease Mechanisms, Biosciences, Brunel University, London, UK

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions