Overview

Microbe, a brand-new, general microbiology textbook intended for upper-division undergraduate and beginning graduate courses, is an exciting introduction to the world of microbes. With a distinct ecological and evolutionary orientation, Microbe invites readers to partake of the most current advances in the field. Written by prominent scientists with practical teaching, textbook writing, and research experience, this new textbook will engage students in the learning process with its clear, reader-friendly style and unique perspective of the field. * Emphasizes the roles of microbes in sustaining all life on Earth * Presents paradigm-driven material in a clear, reader-friendly style * Deals with the complexities of medical microbiology from the standpoint of both the microbe and its human host * Provides unifying frameworks for understanding microbial metabolism and physiology * Offers study questions at the end of each chapter for reinforcement of material covered * Features companion Web site with valuable student resources that is regularly updated by authors

Full Product Details

Author:   Moselio Schaechter ,  Michele Swanson ,  Gemma Reguera ,  John L Ingraham
Publisher:   American Society for Microbiology
Imprint:   American Society for Microbiology
Dimensions:   Width: 21.70cm , Height: 2.50cm , Length: 27.60cm
Weight:   1.658kg
ISBN:  

9781555813208

ISBN 10:   1555813208
Pages:   558
Publication Date:   15 December 2005
Audience:   Professional and scholarly ,  Professional & Vocational
Replaced By:   9781555819125
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   In Print  
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

Table of Contents

Table of Contents Preface About the Authors Study Aids Section I. Microbial Activity 1. The World of Microbes * Introduction * What is a microbe? * Having a long past * Being small * Being many * Growing and persisting * Colonizing every niche and making Earth inhabitable * Shaping the planet * Making a living * Cooperating for complex endeavors * Conclusions * Study questions Section II. Structure and Function 2. Prokaryotic Cell Structure and Function: Envelopes and Appendages * Prokaryotic cells * Microscopes o Newer microscopes Scanned-proximity probe microscopes Molecular stains * Prokaryotes have complex envelopes and appendages * The cell membrane * How the cell membrane is protected o The gram-positive solution o The gram-negative solution o The acid-fast solution o Crystalline surface layers o Bacteria without cell walls: the mycoplasmas o Cell envelopes of the Archaea * Capsules, flagella, and pili: how prokaryotes cope in certain environments o Capsules and slime layers o Flagella o Pili * Study questions 3. Prokaryotic Cell Structure and Function: the Cell Interior * General observations * The nucleoid * The cytoplasm * Inclusions and vesicles o Gas vesicles o Organelles for photosynthesis and chemosynthesis o Carboxysomes o Enterosomes o Storage granules and others * Conclusions * Study questions Section III. Growth 4. Growth of Microbial Populations * Introduction * How to measure growth of a bacterial culture * When should the growth rate be determined? * The law of growth * Balanced growth * Continuous culture * How is the physiology of the cells affected by the growth rate? * Effects of temperature, hydrostatic pressure, osmotic strength, and pH o Temperature Effect on growth rate Classifying the temperature responses of microbes Growth limits at temperature extremes Lethal effects o Hydrostatic pressure o Osmotic pressure o pH * Conclusions * Study questions 5. Making a Cell * Introduction * Growth metabolism: making life from nonlife * Framework of growth metabolism o Making two from one o Assembling cell structures o Making macromolecules o Synthesizing building blocks o Fueling * Global effects of growth metabolism o Earth's chemical cycles o Bioremediation * Summary and plan * Study questions 6. Fueling * Overview of fueling reactions * Getting energy and reducing power o Driving force and its generation o Substrate level phosphorylation and fermentation o Transmembrane ion gradients Respiration Photosynthesis Enzyme pumps Scalar reactions o Oxygen and life * Making precursor metabolites: heterotrophy o Acquiring nutrients Transport through the OM of gram-negative bacteria Transport through the cell membrane o Feeder pathways o Central metabolism Common pathways of central metabolism Auxiliary pathways of central metabolism Diversity and flexibility of central metabolism * Making precursor metabolites: autotrophy o The Calvin cycle o Other CO2-fixing cycles * Summary * Study questions 7. Biosynthesis * Some general observations o Biosynthesis and nutrition o Bacterial studies and biosynthetic pathways o The concept of a biosynthetic pathway * Assimilation of nitrogen o Central actors: glutamate and glutamine o Synthesis of glutamate and glutamine o Getting ammonia o Ammonia from dinitrogen * Assimilation of sulfur * Assimilation of phosphorus * Pathways to building blocks o Amino acids o Nucleotides o Sugars and sugar-like derivatives o Fatty acids and lipids * Summary * Study questions 8. Building Macromolecules * Introduction * DNA o Overview of replication o Initiation of replication o DNA strand elongation o Repair of errors in replication o Termination of replication o Protecting the DNA o Assembly of the nucleoid * RNA

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