Overview
The postgenomic era presents a multitude of challenges for scientists in all areas of science. The information overload from new discoveries in genomics and proteomics highlight how little we really know about the functioning of a cell. The advent of Next-Generation Sequencing technologies promises to make our genetic blueprint available to the common man. The availability of the plethora of biological information has lead to the devel- ment of new areas of science and the coining of new ""omics"" terms including transcr- tomics, methylomics, toxicogenomics, pharmacogenomics, metabolomics, lipidomics, and so on. Remarkable research is being conducted to understand the various aspects of human health and how processes like histone modifcations, promoter usage, alternative splicing, posttranscriptional, and posttranslational modifcations contribute to disease. The advent of systems biology has unifed chemists and biochemists alike in the struggle to eradicate or treat human disease. Microarrays have blossomed into a fast developing and cutting-edge technology that promises to become a major component of personalized medicine. The 1990s witnessed a boom in many areas including genome sequencing, combinatorial chemistry, and c- puters, all of which have contributed to the development of microarray technology from its infancy into a mature tool. The growing potential of this tool is evident from the n- ber of publications since 1991 when Fodor et al. of Affymax (now Affymetrix) frst described the microarray prototype.
Full Product Details
Author: Sridar V. Chittur
Publisher: Humana Press Inc.
Imprint: Humana Press Inc.
Edition: 2010 ed.
Volume: 632
Dimensions:
Width: 17.80cm
, Height: 1.70cm
, Length: 25.40cm
Weight: 1.620kg
ISBN: 9781607616627
ISBN 10: 1607616629
Pages: 285
Publication Date: 18 March 2010
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Hardback
Publisher's Status: Active
Availability: In Print
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Reviews
From the reviews: “Microarray Methods for Drug Discovery is volume number 632 of the Springer Protocols Methods in Biology Series. … it provides detailed experimental protocols for the use of microarrays in a variety of applications. … chapters are obviously highly bespoke and would be of real value to laboratories wishing to establish the method. Finally, the microarray area is now so broad that the non-nucleic acid application of microarrays would justify a methods book in its own right.” (James Sidaway, BTS Newsletter, Issue 37, Winter, 2010) “Methods in Microarrays provide scientists with a complete resource on the most effective tools available for maximizing microarray data in biochemical methods. … Microarrays are extensively used in the effects of compounds on gene expression in cells. This book aims at enlightening individuals of all levels of experience about some of the most common applications of microarrays in drug discovery and development. This book will serve as a reference for students and scientists … .” (Veni Maria Andres Felli, Brazilian Journal of Pharmaceutical Sciences, May, 2010)
From the reviews: Microarray Methods for Drug Discovery is volume number 632 of the Springer Protocols Methods in Biology Series. ! it provides detailed experimental protocols for the use of microarrays in a variety of applications. ! chapters are obviously highly bespoke and would be of real value to laboratories wishing to establish the method. Finally, the microarray area is now so broad that the non-nucleic acid application of microarrays would justify a methods book in its own right. (James Sidaway, BTS Newsletter, Issue 37, Winter, 2010) Methods in Microarrays provide scientists with a complete resource on the most effective tools available for maximizing microarray data in biochemical methods. ! Microarrays are extensively used in the effects of compounds on gene expression in cells. This book aims at enlightening individuals of all levels of experience about some of the most common applications of microarrays in drug discovery and development. This book will serve as a reference for students and scientists ! . (Veni Maria Andres Felli, Brazilian Journal of Pharmaceutical Sciences, May, 2010)
From the reviews: Microarray Methods for Drug Discovery is volume number 632 of the Springer Protocols Methods in Biology Series. ! it provides detailed experimental protocols for the use of microarrays in a variety of applications. ! chapters are obviously highly bespoke and would be of real value to laboratories wishing to establish the method. Finally, the microarray area is now so broad that the non-nucleic acid application of microarrays would justify a methods book in its own right. (James Sidaway, BTS Newsletter, Issue 37, Winter, 2010)
