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Overview"The major histocompatibility complex is the subject of much research in the immunology area. There is interest in the structure of MHC proteins and in their function as antigen-presenting molecules. Many immunology labs are now faced with the prospect of tackling biochemical and genetic techniques in order to study these molecules, and these two ""Practical Approach"" volumes provide an introduction. MHC 2 is complemented by MHC 1." Full Product DetailsAuthor: Nelson Fernandez (Department of Biological and Chemical Sciences, University of Essex) , G. Butcher (Babraham Institute, Cambridge)Publisher: Oxford University Press Australia Imprint: OUP Australia and New Zealand Volume: 181 Dimensions: Width: 15.70cm , Height: 1.50cm , Length: 23.50cm Weight: 0.446kg ISBN: 9780199635559ISBN 10: 0199635552 Pages: 254 Publication Date: 01 January 1998 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Out of Print Availability: In Print  Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock. Table of Contents1: Generation of HLA-specific human monoclonal antibodies 2: Sequencing of proteins isolated by one or two dimensional gel electrophoresis 3: Assembly of MHC molecules: requirements of glycosylation, oxidized glutathione, and peptides 4: Expression, purification, and characterization of recombinant soluble MHC class I molecules 5: The use of pulsed field gel electrophoresis to map the human MHC 6: Derivation and analysis of MHC transgenic mice 7: Imaging of individual cell surface MHC antigens using fluorescent particles 8: Sequence analysis of major histocompatibility molecules 9: Approaches to studying MHC expression in mammals other than primates 10: Techniques to identify the rules governing class II MHC-peptide formationReviewsAuthor InformationDr Nelson Fernandez, Dept of Biological and Chemical Sciences, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, UK. Tel: 01206 873330. Fax: 01206 872592. Email: nelson@essex.ac.uk Dr Geoff Butcher, Babraham Institute, Babraham, Cambridge, UK Tab Content 6Author Website:Countries AvailableAll regions |
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