Overview

"Much research focuses on the question of how information is processed in nervous systems, from the level of individual ionic channels to large-scale neuronal networks, and from ""simple"" animals such as sea slugs and flies to cats and primates. Interdisciplinary methodologies combine a bottom-up experimental methodology with the more top-down-driven computational and modelling approach. This book serves as a handbook of computational methods and techniques for modelling the functional properties of single and groups of nerve cells. The contributions highlight several key trends: firstly, the tightening link between analytical/numerical models and the associated experimental data; the broadening of modelling methods, at both the subcellular level and the level of large neuronal networks that incorporate real biophysical properties of neurons as well as the statistical properties of spike trains; and the organization of the data gained by physical emulation of the nervous system components through the use of very large scale circuit design integration (VLSI) technology. Half of the chapters in this second edition of the text are completely new, while the remaining ones have been thoroughly revised. Many chapters provide an opportunity for interactive tutorials and simulation programs."

Full Product Details

Author:   Christof Koch ,  Idan Segev ,  Terrence J. Sejnowski (Francis Crick Professor, Salk Institute for Biological Studies) ,  Tomaso A. Poggio (Professor, Massachusetts Institute of Technology)
Publisher:   MIT Press Ltd
Imprint:   MIT Press
Edition:   2nd Revised edition
Dimensions:   Width: 18.30cm , Height: 3.80cm , Length: 23.10cm
Weight:   1.430kg
ISBN:  

9780262112314

ISBN 10:   0262112310
Pages:   687
Publication Date:   12 June 1998
Recommended Age:   From 18 years
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   In Print  
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

Table of Contents

Kinetic models of synaptic transmission, Alain Destexhe et al; cable theory for dendritic neurons, Wilfrid Rall, Hagai Agmon-Snir; compartmental models of complex neurons, Idan Segev et al; multiple channels and calcium dynamics, Walter M. Yamada et al; modelling active dendritic processes in pyramidal neurons, Zachary F. Mainen, Terrence J. Sejnowski; calcium dynamics in large neuronal models, Erik De Schutter, Paul Smolen; analysis of neural excitability and oscillations, John Rinzel, Bard Ermentrout; Design and fabrication of analog VLSI neurons, Rodney Douglas, Misha Mahowald; principles of spike train analysis, Fabrizio Gabbiani, Christof Koch; modelling small networks, Larry, F. Abbott, Eve Marder; spatial and temporal processing in central auditory networks, Shihab Shamma; simulating large networks of neurons, Alexander D. Proptopapas et al; modelling features selectivity in local cortical circuits, David Hansel, Haim Sompolinsky; numerical methods for neuronal modelling, Michael V. Mascagni, Arthur S. Sherman.

Reviews

An admirable concentration of expertise on state-of-the-art neuronal modeling techniques--a must on the bookshelf of computational neuroscientists and theoretical neurobiologists. --Wolf Singer, M.D., Ph.D., Max-Planck-Institute for Brain Research

Author Information

Christof Koch is Professor of Biology and of Engineering at the California Institute of Technology and Chief Scientific Officer of the Allen Institute for Brain Science in Seattle. He is the author of The Quest for Consciousness and other books.

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