Methods in Bioengineering: Organ Preservation and Reengineering

Author:   Charles Lee ,  Korkut Uygun
Publisher:   Artech House Publishers
Edition:   Unabridged edition
ISBN:  

9781608070138


Pages:   280
Publication Date:   31 May 2011
Format:   Hardback
Availability:   In Print   Availability explained
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Methods in Bioengineering: Organ Preservation and Reengineering


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Overview

Written and edited by recognized experts in the field, the new ""Artech House Methods in Bioengineering book series"" offers detailed guidance on authoritative methods for addressing specific bioengineering laboratory challenges. Offering a highly practical presentation of each topic, each book provides research engineers, scientists, and students with step-by-step procedures, clear examples, and effective ways to overcome possible problems. This first-of-its-kind volume addresses the important challenge of organ preservation and reengineering. This book presents cutting-edge techniques for damaged livers and hearts via normothermic perfusion, hypothermic machine perfusion for the liver, kidney and pancreas, and imaging techniques to assess the viability of injured kidneys. Professionals and researchers also find methods to decellularize whole organs to create scaffolds for tissue engineering. Moreover, this book presents an approach to enhancing hepatocyte recovery from marginal livers.

Full Product Details

Author:   Charles Lee ,  Korkut Uygun
Publisher:   Artech House Publishers
Imprint:   Artech House Publishers
Edition:   Unabridged edition
Dimensions:   Width: 18.30cm , Height: 2.00cm , Length: 25.90cm
Weight:   0.771kg
ISBN:  

9781608070138


ISBN 10:   1608070131
Pages:   280
Publication Date:   31 May 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Introduction. Preservation - Normothermic Machine Perfusion of the Liver. Heart Preservation. Hypothermic Machine Perfusion of the Kidneys. Methods of Cardiac Oxygen Persufflation. Vascular Oxygen Persufflation for Preservation and Reconditioning of Marginal Liver Grafts. Use of Optical Imaging and Spectroscopy in Assessment of Organ Perfusion. Reengineering - Preparation of a Transplantable Liver Graft by Recellularization of Decellularized Whole Organs. Engineering Lung Tissue. Ex Vivo Perfusion of Rat Liver Grafts for Hepatocyte Retrieval.

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Author Information

Korkut Uygun is the leader of the Organ Engineering Group at Massachusetts General Hospital, where he was instrumental in developing a technique that promises to allow growth of transplantable replacement livers. Dr. Uygun received his Ph.D. in chemical engineering from Wayne State University. Charles Y. Lee is an associate professor in the Department of Medical Engineering at the University of North Carolina, Charlotte. Dr. Lee earned his Ph.D. in mechanical engineering from the University of California, Berkeley.

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