Overview

Neuroscience research in alcohol-related disorders has made remarkable progress in the last two decades. The advances are due, in great part, to the large array of powerful biomedical, bioengineering, and computational biological techniques that are now employed. To date, there has not been a comprehensive text that covers recently developed methods in alcohol-related research. Methods in Alcohol-Related Neuroscience Research provides up-to-date technical guidance for investigators doing research at the molecular, cellular, systems, and behavioral levels. These techniques include a wide variety of approaches, ranging from gene mapping and examination of molecular interactions of alcohol at the sub-cellular level to recording of neural activities in freely-behaving animals and imaging alcohol effects on the living human brain. Written by a panel of experts, Methods in Alcohol-Related Neuroscience Research not only provides information of a technical nature but also gives an overview of the many areas in investigating the effects of alcohol on the brain.

Full Product Details

Author:   Steven N. Treistman ,  Yuan Liu ,  Sidney A. Simon ,  Nandor Ludvig (State University of New York)
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
Volume:   14
Dimensions:   Width: 15.60cm , Height: 2.80cm , Length: 23.40cm
Weight:   1.000kg
ISBN:  

9780849302039

ISBN 10:   084930203
Pages:   416
Publication Date:   14 February 2002
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Out of stock  

Table of Contents

Quantitative Trait Locus Mapping in Mice. Knockout and Knockin Mice. Molecular Studies by Chimeragenesis and Mutagenesis. Combining Patch-Clamp Recording and Gene Profiling in Single Neurons. Quantitative Analysis of Neurotransmitter Receptor Expression with Antibody-Based Techniques. Artificial Bilayer Techniques in Ion Channel Study. Rapid Drug Superfusion and Kinetic Analysis. Electrophysiological Assessment of Synaptic Transmission in Brain Slices. Cognitive Correlates of Single Neuron Activity in Task-Performing Animals. Multichannel Neural Ensemble Recording during Alcohol Self-Administration. Combined Single-Neuron Recording and Microdialysis in the Brain of Freely-Behaving Animals. Quantitative Microdialysis for in vivo Studies of Pharmacodynamics. Structural MRI of the Human Brain. Biochemical, Functional and Microstructural MRI.

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Yuan Liu, David M. Lovinger

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