Overview

Metastasis (spread of cancer in the body) is the main cause of death for patients with breast cancer, the leading female tumour in the industrialised countries and developing countries alike. The biology and treatment of breast cancer metastasis remains an active area of scientific and clinical investigation. Written by experts in the subject area, the book has covered a broad range of topics in the metastasis of breast cancer, from genetics, biology to clinical management. Main topics include genetic control, biology, growth factors, cell adhesion, cell motility and invasion, natures of bone metastasis, sentinel node therapies, hormonal links, new biomarkers and detection of micrometastasis, and diagnosis The book also covers the current treatment options including surgical management, chemotherapy and hormonal therapies. This timely book provides the current knowledge in the area of breast cancer metastasis and will be of important reading material for oncologists, radiologists, cancer researchers, biologists and health worker.

Full Product Details

Author:   R.E. Mansel ,  Oystein Fodstad ,  Wen G. Jiang
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2008 ed.
Volume:   11
Dimensions:   Width: 15.50cm , Height: 2.50cm , Length: 23.50cm
Weight:   1.790kg
ISBN:  

9781402058660

ISBN 10:   1402058667
Pages:   435
Publication Date:   14 June 2007
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Metastasis of breast cancer: an introduction.- The genetic control of breast cancer metastasis.- BRCA1 in initiation, invasion, and metastasis of breast cancer: a perspective from the tumor microenvironment.- Cell motility and breast cancer metastasis.- Tight junctions and metastasis of breast cancer.- Cell adhesion molecules in breast cancer invasion and metastasis.- Endocrine resistance and breast cancer invasion.- The role of aromatase and other oestrogen producing enzymes in mammary carcinogenesis.- The role of the HGF regulatory factors in breast cancer.- The insulin-like growth factor-1 ligand in breast cancer management.- Lymphangiogenesis and metastatic spread of breast cancer.- Breast cancer secreted factors alter the bone microenvironment.- Cyclooxygenease-2 and breast cancer.- Prognostic and predictive factors in human breast cancer.- Molecular imaging in metastatic breast cancer.- Detection of disseminated tumor cells in the bone marrow and blood of breast cancer patients.- Sentinel lymph node biopsy in early-stage breast cancer.- Surgical management of patients with metastatic breast cancer.- Therapeutic aspect of metastatic breast cancer: chemotherapy.- The diagnosis and treatment of bone metastases in breast cancer.- Hormonal therapies of metastatic breast cancer: the past and the present.

Reviews

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions