Membrane Defenses Against Attack by Complement and Perforins
Author:   Charles J. Parker
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Volume:   v.178
ISBN:  

9783540546535


Pages:   196
Publication Date:   11 June 1992
Format:   Hardback
Availability:   Out of stock   Availability explained
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Membrane Defenses Against Attack by Complement and Perforins


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Overview

In this volume a comprehensive review of membrane proteins that regulate complement and perforin-mediated cytolysis is presented. A detailed analysis is provided of the biochemical, molecular, and functional features of these proteins. The glycosyl-phosphatidyl-inositol linked proteins are covered, with emphasis placed on the functional importance of this type of membrane anchor. Further chapters include reviews of the effects of complement activation on cells that are metabolically active, and of the regulation of cell killing by cytotoxic lymphocytes, considering the similarities and disparities between the complement and perforin systems. The therapeutic use of recombinant CRI for immune-mediated pathophysiological processes is discussed in a separate section.

Full Product Details

Author:   Charles J. Parker
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Volume:   v.178
Weight:   0.435kg
ISBN:  

9783540546535


ISBN 10:   3540546537
Pages:   196
Publication Date:   11 June 1992
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

List of Contents.- Regulation of Complement by Membrane Proteins: An Overview.- Decay Accelerating Factor (CD55).- Complement Receptor Type 1.- Membrane Cofactor Protein.- Membrane Inhibitor of Reactive Lysis.- Homologous Restriction Factor.- The Effects of Complement Activation on Platelets.- Effects of the Membrane Attack Complex of Complement on Nucleated Cells.- Glycosyl-Phosphatidylinositol Anchoring of Membrane Proteins.- Paroxysmal Nocturnal Hemoglobinuria.- Perforin-Structure, Function, and Regulation.

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