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OverviewThis work is a guidebook for clinicians who are involved in treating depressive patients and also serves the research scientists who are working on the psychopharmacological mechanisms of antidepressant actions and psychopathological mechanisms underlying mood disorders. Mood disorders such as major depressive disorder (MDD), bipolar disorder (BPD) and seasonal affective disorder (SAD) are the most disabling disorders that are among the most expensive of all medical illnesses. The pathophysiology of mood disorders is very complex and involves many mechanisms like circadian rhythm disruption, sleep abnormalities, melatonin rhythm abnormalities and alterations in melatonin receptor mechanisms, abnormalities in monoaminergic neurotransmitter mechanisms, glutamatergic release mechanisms, hippocampal neurogenesis, and abnormal immune and cytokine release mechanisms. Many antidepressants that are in clinical use today including the recently introduced novel agents like agomelatine or other antidepressants cause clinical remission by resynchronizing disrupted circadian rhythms and melatonin receptor functions, enhancing monoaminergic neurotransmission, promoting hippocampal neurogenesis, and regulating immune mechanisms. This book explains various etiological factors that are involved in the pathogenesis of mood disorders and the mechanisms of therapeutic actions of antidepressants including the recently introduced agomelatine and other antidepressants that exhibit rapid onset of action with greater efficacy and fewer side effects. . Full Product DetailsAuthor: Francisco Lopez-Munoz , Venkataramanujam Srinivasan , Domenico de Berardis , Cecilio AlamoPublisher: Springer, India, Private Ltd Imprint: Springer, India, Private Ltd Edition: Softcover reprint of the original 1st ed. 2016 ISBN: 9788132238423ISBN 10: 8132238427 Pages: 921 Publication Date: 20 July 2018 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand We will order this item for you from a manufactured on demand supplier. Table of ContentsReviewsAuthor InformationProf.Venkataramanujan Srinivasan,Msc, Ph.D MAMS SRI SATHYA SAI MEDICAL EDUCATIONAL AND RESEARCH FOUNDATION An International Medical Sciences Research Study Center PrasanthiNilayam , KOVAI, Coimbatore, Tamilnadu, INDIA Tab Content 6Author Website:Countries AvailableAll regions |