Overview

Fullerenes and nanotubes are two classes of carbon structures or allotropes, which were discovered about 17 years ago. Since that time, many chemical derivatives have been synthesized using fullerenes and nanotubes as building blocks. Particularly promising was the theory that the chemical properties of fullerenes, and certain derivatives, made them likely candidates for anticancer drugs, inhibitors of viruses such as HIV, or even as anti-bacterials. Their cyctotoxicity can also be controlled by specific circumstances. In addition, the funtionalization of nanotubes has not only produced relatively simple derivatives, but also complex hybrids with biological macromolecules, which show unique supramolecular architecture and which are promising in many medical applications. The application of fullerenes and nanotubes in medicine is at the frontier of our knowledge, thus the work in this field represents the basis for future novel developments.

Full Product Details

Author:   Franco Cataldo ,  Tatiana da Ros
Publisher:   Springer
Imprint:   Springer
Edition:   2008
Volume:   1
Weight:   0.606kg
ISBN:  

9789048177363

ISBN 10:   9048177367
Pages:   408
Publication Date:   02 January 2013
Audience:   Professional and scholarly ,  Professional and scholarly ,  Professional & Vocational ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

Twenty Years of Promises: Fullerene in Medicinal Chemistry.- Biomedical Applications of Functionalised Carbon Nanotubes.- Antioxidant Properties of Water-Soluble Fullerene Derivatives.- Fullerenes as Photosensitizers in Photodynamic Therapy.- Photodynamic Inactivation of Enveloped Viruses by Fullerene: Study of Efficacy and Safety.- Effects of Photoexcited Fullerene C60-Composites in Normal and Transformed Cells.- Biological Effects in Cell Cultures of Fullerene C60: Dependence on Aggregation State.- Gadolinium Endohedral Metallofullerene-Based MRI Contrast Agents.- Biomolecules Functionalized Carbon Nanotubes and Their Applications.- Applications of Carbon-Based Nanomaterials for Drug Delivery in Oncology.- Visualization of Carbon Nanoparticles Within Cells and Implications for Toxicity.- Pharmacological Applications of Biocompatible Carbon Nanotubes and Their Emerging Toxicology Issues.- Solubility of Fullerenes in Fatty Acids Esters: A New Way to Deliver In Vivo Fullerenes. Theoretical Calculations and Experimental Results.- New Approach to QSPR Modeling of Fullerene C60 Solubility in Organic Solvents: An Application of SMILES-Based Optimal Descriptors.- Functionalized Nanomaterials to Sense Toxins/Pollutant Gases Using Perturbed Microwave Resonant Cavities.- Cellular Nanotubes: Membrane Channels for Intercellular Communication.

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