Overview

Mechanochemical Organic Synthesis is a comprehensive reference that not only synthesizes the current literature but also offers practical protocols that industrial and academic scientists can immediately put to use in their daily work. Increasing interest in green chemistry has led to the development of numerous environmentally-friendly methodologies for the synthesis of organic molecules of interest. Amongst the green methodologies drawing attention, mechanochemistry is emerging as a promising method to circumvent the use of toxic solvents and reagents as well as to increase energy efficiency. The development of synthetic strategies that require less, or the minimal, amount of energy to carry out a specific reaction with optimum productivity is of vital importance for large-scale industrial production. Experimental procedures at room temperature are the mildest reaction conditions (essentially required for many temperature-sensitive organic substrates as a key step in multi-step sequence reactions) and are the core of mechanochemical organic synthesis. This green synthetic method is now emerging in a very progressive manner and until now, there is no book that reviews the recent developments in this area.

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9780128021842

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Dr. Davor Margetić is senior research scientist and acting head of the division of organic chemistry and biochemistry at Ruđer Bošković research Institute in Zagreb, Croatia. He is the head of the laboratory for physical organic chemistry and Professor of physical organic chemistry at Rijeka University.He graduated with a degree in chemical engineering at Zagreb University and continued in the field of organic syntheses with Ms.Sc. and Ph.D. studies in the field of theoretical and physical organic chemistry (Zagreb). The completion of his Ph.D. was followed by a postdoctoral research studies at the Centre for Molecular Architecture, Central Queensland University, Australia. There he worked with Professors Ronald Warrener and Doug Butler for 9 years (synthetic organic and computational chemistry). In 2002, he returned to Croatia to take up a position at RBI, and in 2009 he was promoted to senior research scientist (an equivalent of full professor at the university). Research interests of Dr. Margetić include the synthesis and investigation of theoretically interesting molecules, the study of reaction mechanisms, computational organic chemistry, and the development of environmentally-friendly organic reactions using novel techniques (extreme high pressures, microwave irradiation, and mechanochemistry). During his scientific career, Dr. Margetić has published 90 research papers, 42 electronic conference papers, and 9 book chapters. He has authored one book: ""Microwave Assisted Cycloaddition Reactions"" with Nova Science Publishers, New York (2011); and edited two books: Croatica Chemica ActA Special issue dedicated to the 70th birthday of Professor Z. B. Maksić (2009), and Special issue dedicated to 70th birthday of Professor M. Eckert-Maksić (2014). Dr. Vjekoslav Štrukil is a research associate at the laboratory for Physical Organic Chemistry at Rudjer Bošković Institute in Zagreb, Croatia. He obtained his B.Sc. (2005) and Ph.D. (2010) degrees from the Faculty of Science, University of Zagreb, Croatia. During several short visits to the Department of Chemistry, Cambridge University, United Kingdom (2009-2011), Dr. Štrukil started research in mechanochemistry and continued his training as a postdoctoral fellow at the Department of Chemistry, McGill University in Montreal, Canada, (2012-2013) working under the supervision of Professor Tomislav Friščić. In 2013, he received the Annual Award for Junior Researchers in Croatia. Apart from organic mechanochemistry, his scientific interests also include the synthesis and reactivity of guanidine and polyguanide derivatives, theoretical and experimental study of their physico-chemical properties, and the application of green synthetic methods in organic chemistry. Dr. Štrukil has co-authored 21 scientific papers.

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