Overview

This textbook provides an introduction to an important but often neglected area within the toxicological sciences. It gives insights into the processes and mechanisms underlying the toxicity of chemicals and explains how foreign compounds (drugs, environmental pollutants, industrial chemicals) exert their potentially damaging effects on cells and tissues.; Reductionism to cellular and molecular mechanisms is one of the cornerstones of modern toxicology, forming the basis for a better understanding of individual toxic effects and providing an important tool for human risk assessment. The features of this book include summaries of the main learning points and question-and-answer reviews at the end of each chapter.; Mechanistic Toxicology incorporates advances in molecular biology and it develops concepts for the reader in a logical way. It also illustrates, using many examples and complementary background information, how a better understanding of these mechanistic pathways helps in estimating potential risk to human health.

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9781280202339

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