Overview

This book is an introduction to the mechanical properties, the force generating capacity, and the sensitivity to mechanical cues of the biological system. To understand how these qualities govern many essential biological processes, we also discuss how to measure them. However, before delving into the details and the techniques, we will first learn the operational definitions in mechanics, such as force, stress, elasticity, viscosity and so on. This book will explore the mechanics at three different length scales – molecular, cellular, and tissue levels – sequentially, and discuss the measurement techniques to quantify the intrinsic mechanical properties, force generating capacity, mechanoresponsive processes in the biological systems, and rupture forces.

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9781643273938

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Seungman Park is currently a Postdoctoral Associate at Johns Hopkins University, MD. Dr. Park Received his Ph.D. degree in Mechanical Engineering from Purdue University, IN, in 2014. His research area is tissue engineering, cell mechanics, and mechanobiology. Dr. Park is a member of American Heart Association, American Physical Society, American Society of Cell Biology and Biophysical Society. He is also the awardee of Maryland Stem Cell Research Fund Fellowship. Yun Chen is an assistant professor in the Department of Mechanical Engineering, at Johns Hopkins University, MD. She is specialized in developing multi-scale, multi-modal imaging tools to study how mechanics integrates with other biophysical and biochemical factors to sustain normal physiology or to cause pathology.

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