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OverviewThis open access book revolves around predictive mathematical modelling and simulation of brain multiphysics with an emphasis on cerebrospinal fluid flow and solute transport in and around the human brain. The book consists of 10 self-contained and relatively short chapters, each offering a rapid introduction to a key problem or topic, supported by open source software. Readers will gain insights into state-of-the-art mathematical tools and techniques for modelling and simulation of brain multiphysics ranging from classical finite element approaches, network-based modelling techniques and deep neural networks. The target audiences are researchers in applied mathematics, scientific computing, biophysics, bioengineering or computational neuroscience interested in a compact introduction to image-based computational modeling of brain multiphysics and cutting-edge available tools. Full Product DetailsAuthor: Jørgen S. Dokken , Kent-Andre Mardal , Marie E. Rognes , Lars Magnus ValnesPublisher: Springer Nature Switzerland AG Imprint: Springer Nature Switzerland AG Volume: 7 ISBN: 9783032006783ISBN 10: 3032006783 Pages: 150 Publication Date: 11 January 2026 Audience: College/higher education , Postgraduate, Research & Scholarly Format: Paperback Publisher's Status: Forthcoming Availability: Not yet available This item is yet to be released. You can pre-order this item and we will dispatch it to you upon its release. Table of Contents1 From brain physiology to brain physics.- 2 Meshing the intracranial compartments: Cerebellum, cerebrum, brainstem and cerebrospinal fluid.- 3 Segmenting, meshing and modeling CSF spaces.- 4 The pulsating brain: An interface-coupled fluid-poroelasticinteraction model of the cranial cavity.- 5 Quantifying cerebrospinal fluid tracer concentration in the brain.- 6 Signal increase ratio prediction with CNNs.- 7 Estimating molecular transport parameters using inverse PDEmodels.- 8 Two-compartment modeling of tracer transport in the brain.- 9 An introduction to identifying velocity fields from contrast imaging via PDE-constrained optimization. 10 An introduction to network models of neurodegenerative diseases.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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