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OverviewThis monograph aims to present a unified approach to using mathematical models in the study of qualitative and quantitative regularities of immune response dynamics in infectious diseases within individual organisms. These mathematical models are formulated as systems of delay-differential equations. Simple mathematical models of infectious diseases, antiviral immune response and antibacterial response are developed and applied to the study of hepatitis B, influenza A, infectious bacterial pneumonia, and mixed infections. Particular attention is paid to the development of efficient computational procedures for solving the initial value problem for stiff delay-differential equations and to the parameter identification problem. Adjoint equations and the perturbation theory are used for the sensitivity analysis. This book is aimed at mathematicians and specialists in immunology and infectious diseases. It can also be used as a textbook for postgraduate students, bridging the gap between mathematics, immunology and infectious diseases research. Full Product DetailsAuthor: Guri I. MarchukPublisher: Springer Imprint: Springer Edition: 1997 ed. Volume: 395 Dimensions: Width: 15.50cm , Height: 2.00cm , Length: 23.50cm Weight: 1.510kg ISBN: 9780792345282ISBN 10: 0792345282 Pages: 350 Publication Date: 30 April 1997 Audience: College/higher education , Professional and scholarly , Postgraduate, Research & Scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Awaiting stock ![]() The supplier is currently out of stock of this item. It will be ordered for you and placed on backorder. Once it does come back in stock, we will ship it out for you. Table of Contents1. General Knowledge, Hypotheses, and Problems.- 2. Survey of Mathematical Models in Immunology.- 3. Simple Mathematical Model of Infectious Disease.- 4. Mathematical Modeling of Antiviral and Antibacterial Immune Responses.- 5. Identification of Parameters of Models.- 6. Numerical Realization Algorithms for Mathematical Models.- 7. Viral Hepatitis B.- 8. Viral and Bacterial Infections of Respiratory Organs.- 9. Model of Experimental Influenza Infection.- 10. Adjoint Equations and Sensitivity Study for Mathematical Models of Infectious Diseases.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |