Mathematical Modeling and Scale-Up of Liquid Chromatography: With Application Examples
Author:   Tingyue Gu
Publisher:   Springer International Publishing AG
Edition:   2nd ed. 2015
ISBN:  

9783319307602


Pages:   207
Publication Date:   14 April 2015
Format:   Paperback
Availability:   In Print   Availability explained
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Mathematical Modeling and Scale-Up of Liquid Chromatography: With Application Examples


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Author:   Tingyue Gu
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   2nd ed. 2015
Dimensions:   Width: 15.50cm , Height: 1.20cm , Length: 23.50cm
Weight:   0.502kg
ISBN:  

9783319307602


ISBN 10:   3319307606
Pages:   207
Publication Date:   14 April 2015
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Introduction.- Literature Review.- General Multicomponent Rate Models for Column Liquid Chromatography.- Parameter Estimation.- Mass Transfer Effects in Liquid Chromatography Simulation.- Interference Effects in Multicomponent Chromatography.- System Peaks in Multicomponent Elution.- Modeling and Scale-up of Size Exclusion Chromatography.- Modeling of LC with cored beads.- Modeling of Slow Kinetics and Affinity Chromatography.- Multicomponent Adsorption with Uneven Saturation Capacities.- Modeling of Multicomponent Gradient Elution.- Modeling of Ion-Exchange Chromatography.- Multicomponents Radial Flow Chromatography.

Reviews

This book is a welcome addition for those who want to better understand the modeling of nonlinear liquid chromatography. ... The combination of this book with the Chromulator software makes this a good teaching resource for specialized undergraduate or graduate chemistry as well as chemical engineering courses. ... This book is definitely written in the language of chemical engineers, but chemists and other users of chromatography will also appreciate its capacity to improve their understanding of the modeling of chromatography. (Attila Felinger, Analytical and Bioanalytical Chemistry, April, 2016)


Author Information

Dr. Tingyue Gu is a professor in the Department of Chemical & Biomolecular Engineering at Ohio University. He obtained his PhD degree in chemical engineering from Purdue University in 1990. His PhD work was devoted to liquid chromatography (LC) theories and modeling. Dr. Gu has solved a series of LC models numerically for various forms of LC and developed a comprehensive software package with graphical user interface. His software has been used in over 34 countries by numerous people. The software is offered for free for academic applications. It has also been commercially licensed by major companies including leading biotech and pharmaceutical companies. The software has been successfully used for product development with huge savings in time through simulation. Apart from LC, his current research also encompasses bioenergy, biofilm electrochemistry, biocorrosion, and microbial fuel cells.

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