Overview

This collection contains papers by participants in the seminar on mathematical methods in molecular biology who worked for several years at the Laboratory of Molecular Biology and Bioorganic Chemistry (now the Institute of Physical and Chemical Problems in Biology) at Moscow State University. The seminar united mathematicians and biologists around the problems of biological sequences. The collection includes original results as well as expository material and spans a range of perspectives, from purely mathematical problems to algorithms and their computer realizations. For this reason, the book is of interest to mathematicians, statisticians, biologists, and computational scientists who work with biopolymer sequences.

Full Product Details

Author:   S. Gindikin
Publisher:   American Mathematical Society
Imprint:   American Mathematical Society
Volume:   No. 8
Weight:   0.539kg
ISBN:  

9780821866016

ISBN 10:   082186601
Pages:   150
Publication Date:   30 December 1992
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   To order  
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Table of Contents

I. Some problems of mathematical statistics On the optimality of the Dayhoff matrix for computing the similarity score between fragments of biological sequences by A. M. Leontovich On the distribution of the maximum similarity score for fragments of two random sequences by V. I. Piterbarg II. Surveys and methodology Computer functional analysis of nucleotide sequences: Problems and approaches by M. S. Gelfand Comparative analysis of biopolymer sequences: Reflections on the validity of the methodology and the underlying general principles by E. V. Koonin III. Methods and algorithms A new method for recognition of structural and functional motifs in protein sequences based on the principal component analysis of profiles of physico-chemical properties by D. R. Davydov, I. Erlikh, E. E. Klotz, and V. G. Fridman Prediction of protein-coding regions in DNA of higher Eukaryotes by M. S. Gelfand DNA physical mapping, flows in networks and minimum cycles mean in graphs by P. Pevzner Fast algorithm for optimal aligning of symbol sequences by M. A. Roytberg IV. Software GeneBee: The program package for biopolymer structure analysis by L. I. Brodsky, A. V. Vassilyev, Ya. L. Kalaydzidis, Yu. S. Osipov, R. L. Tatuzov, and S. I. Feranchuk Data compression and the use of vector operations for the fast search problems in analysis of biological sequences by R. L. Tatuzov and T. A. Mamikonova Organization and storage of information in molecular genetics data banks by R. L. Tatuzov and T. A. Mamikonova.

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