Overview

Reflecting the embryonic state of the field, the first edition of Dermatoxicology, published in 1977, numbered 567 pages. Now the foundational reference in dermal toxicology, this seventh edition consists of 1,032 pages and defines what was once a largely intuitive field but has evolved into an established science of metrics and mechanisms. Updated and expanded to reflect the latest developments, the seventh edition includes fundamental information on the mechanisms of action of toxic substances on the skin and practical information on the many methods for evaluating dermal toxicity. Unparalleled in its coverage and broad in scope, with the addition of 34 new chapters, this volume keeps pace with the expanding science. A perennial bestseller, this definitive text explores the latest developments in the field. With contributions from leading international experts, it continues the tradition of providing unsurpassed theoretical and practical guidance.

Full Product Details

Author:   Francis Nicholas Marzulli ,  Hongbo Zhai (University of California, USA) ,  Howard I Maibach ,  Kla Wilhelm
Publisher:   Taylor & Francis Inc
Imprint:   Productivity Press
Edition:   7th Revised edition
ISBN:  

9781420009774

ISBN 10:   142000977
Pages:   1048
Publication Date:   December 2008
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Replaced By:   9781841848570
Format:   Electronic book text
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Pharmacogenetics and Dermatology, E.E. Lee and H.I. Maibach Ethnic Differences in Skin Properties the Objective Data, S. Saggar, N.O. Wesley, M. Moulton-Levy, and H.I. Maibach Occlusion and Barrier Function, H. Zhai and H.I. Maibach Anatomical Factors Affecting Barrier Function, N.A. Monteiro-Riviere Percutaneous Penetration Enhancers: An Overview, H.-Y. Thong, H. Zhai, and H.I. Maibach Percutaneous Absorption of complex Chemical Mixtures, J.E. Riviere Percutaneous Absorption: Short-Term Exposure, Lag Time, Multiple Exposure, Model Variations, and Absorption from Clothing, R.C. Wester and H.I. Maibach Lipids of the Permeability Barrier, P.W. Wertz Chemical Partitioning Into Powdered Human Stratum Corneum: A Useful In Vitro Model for Studying Interaction of Chemical and Human Skin, X. Hui, R.C. Wester, H. Zhai, A.K. Cashmore, S. Barbadillo, and H.I. Maibach Sensitive Skin, H. Loffler, C. Weimer, I. Effendy and H.I. Maibach Transdermal Drug Delivery System, C.Y. Levin and H.I. Maibach Iontophoresis: From Historical Perspective to Its Place in Modern Medicine, A.N. Anigbogu and H.I. Maibach Irritant Dermatitis Clinical Heterogeneity and Contributing Factor, S. Weltfriend and H.I. Maibach Systemic Contact Dermatitis, N.K Veien, T. Menne and H.I. Maibach Allergic Contact Dermatitis, F.N. Marzulli and H.I. Maibach Mechanisms of Allergic and Irritant Contact Dermatitis, I. Ale and H.I. Maibach Occupational Allergic Contact Dermatitis: Rational Work-Up, I.S. Ale and H.I. Maibach Systemic Toxicity, P. Hewitt and H.I. Maibach Concepts in Molecular Dermatotoxicology, H.F. Merk, J. Abel, J.M. Baron, and J. Krutmann Molecular Basis of Allergic Contact Dermatitis, J.-P. Lepoittevin and V Berl Photoirritation (Phototoxicity, Phototoxic Dermatitis), N. Moulton-Levy and H.I. Maibach Permeability of the Skin for Metal Compounds, with Focus on Nickel and Copper, J.J. Hostnek Chemically Induced Scleroderma, G.G. Russo Chemical Agents that Cause Depigmentation, S. Sohrabian and H.I. Maibach Carcinogenesis: Current Trends in Skin Cancer Research, K. Auborn Retinoids and Mechanisms of Their Toxicity, W.J. Cunningham Mechanisms in Cutaneous Drug Hypersensitivity Reactions, M. Goncalo and D.P. Bruynzeel Drug Induced Ocular Phototoxicity, J.E. Roberts Water: Is It An Irritant? T.-F. Tsai Sodium Lauryl Sulfate, C.H. Lee and H.I. Maibach Factors Influencing the Applied Amount of Topical Preparations Tanzima Islam, N.V. Matveev and H.I. Maibach Barrier Creams, H. Zhai and H.I. Maibach OECD Guidelines for Testing of Chemicals, K.-P. Wilhelm and H.I. Maibach Methods for In Vitro Percutaneous Absorption, R.L. Bronaugh Percutaneous Absorption of Hazardous Substances from Soil and Water, R.C. Wester and H.I. Maibach Pesticide Percutaneous Absorption and Decontamination, D. Zaghi, R.C. Wester and H.I. Maibach Tape Stripping Method versus Stratum Corneum, M.J. Choi, H. Zhai, J.-H. Kim, and H.I. Maibach Parameters Influencing Stratum Corneum Removal by Tape Stripping, H. Loffler, C. Weimer, F. Dreher, and H.I. Maibach Quantification of Stratum Corneum Removed by Tape Stripping, F. Dreher Isolated Perfused Porcine Skin Flap, J.E. Riviere Physiologically-Based Pharmacokinetic Modeling, J.N. McDougal Methods for In Vitro Skin Metabolism Studies, R.L. Bronaugh Predictive Toxicology Methods for Transdermal Delivery Systems, A. Chester, W.-Q. Lin, M. Prevo, M. Cormier and J. Matriano Animal, Human, and In Vitro Test Methods for Predicting Skin Irritation, C.Y. Levin and H.I. Maibach Kawai Method for Testing Irritation, K. Kawai Analysis of Structural Change in Intercellular Lipids of Human Stratum Corneum Induce by Surfactants: Electron Paramagnetic Resonance (EPR) Study, Y. Kawasaki, J.-I. Mizushima, and H.I. Maibach Water and Saline Compresses in the Treatment of Irritant Contact Dermatitis: A Review of the Literature, C.Y. Levin and H.I. Maibach Reaction of Skin Blood Vessels to Successive Insults on Normal and Irritated Human Skin, E. Tur and H.I. Maibach The Specificity of Retinoid-Induced Irritation and Its Role in Clinical Efficacy, J.L. MacGregor and H.I. Maibach Topical Corticosteroids in the Treatment of Irritant Contact Dermatitis- Do They Work? C.Y. Levin and H.I. Maibach Tests for Sensitive Skin, A. Pelosi, E. Berardesca, and H.I. Maibach Test Methods for Allergic Contact Dermatitis in Animals, G. Klecak Test Methods for Allergic Contact Dermatitis in Humans, F.N. Marzulli and H.I. Maibach Allergic Contact Dermatitis Elicitation Thresholds of Potent Allergens in Human, E. Jerschow, J.J. Hostnek, and H. I. Maibach Allergic Contact Dermatitis to Topical Anesthetics: A Cross Sensitization Phenomenon, C.J. Dannaker, E. Austin and H.I. Maibach Contact Urticaria and Anaphylaxis to Chlorhexidine: Overview, C. Heinemann, R. Sinaiko, and H.I. Maibach Immunoadjuvants in Prospective Testing for Contact Allergens, H.C. Maguire, Jr. The Local Lymph Node Assay, I. Kimber, R.J. Dearman, C.J Betts, D.A. Besketter, C.A. Ryan, and G.F. Gerberick Iontophoresis in Humans: Regional Variations in Skin Barrier Function And Cutaneous Irritation, J. Singh, B. Medi, B. Sage, and H.I. Maibach Contact Urticaria and the Contact Urticaria Syndrome (Immediate Contact Reactions), S. Amin, A. Lahti, and H.I. Maibach In Vitro Approaches to the Assessment Skin Irritation and Phototoxicity of Topically Applied Materials, D.A. Basketter Photoirritation (Phototoxicity) Testing in Humans, H.I. Maibach and F.N. Marzulli Measuring and Quantifying Ultraviolet Radiation Exposure, D.H. Sliney Determination of Subclinical Changes of Barrier Function, V. Charbonnier, M. Paye, and H.I. Maibach Assessing the Validity of Alternative Methods for Toxicity Testing - The Role and Activities of ECVAM, T. Hartung and V. Zuang Animal Models of Contact Urticaria, A.I. Lauerma and H.I. Maibach Diagnostic Tests in Dermatology: Patch and Photopatch Testing and Contact Urticaria, S. Amin, A.L. Lauerma and H.I. Maibach Cosmetic Reactions, B.S. Modjtahedi, J.R. Toro, P. Engasser and H.I. Maibach Decreasing Allergic Contact Dermatitis Frequency Through Dermatotoxicologic and Epidemiologic Based Intervention? N.O. Wesley and H.I. Maibach Cutaneous Corticosteroid-Induced Glaucoma, N. Branco, B.C. Branco, J. Mallon, and H.I. Maibach Evaluating Efficacy of Barrier Creams: In Vitro and In Vivo Models, H. Zhai and H.I. Maibach Light-induced Dermal Toxicity: Effects on the Cellular and Molecular Levels, A. Kornhauser, W.G. Wamer and L.A. Lambert Failure of Standard Test Batteries for the Detection of Genotoxic Activity of Some Chemicals Used in Dermatological and Cosmetic products, G. Brambilla and A. Martelli Exogenous Ochronosis, An Update, C.Y. Levin and H.I. Maibach Diagnostic Patch Test: The Science and The Art, I.S. Ale and H.I. Maibach Irritant and Allergic Contact Dermatitis Treatment, H. Zhai, A. Anigbogu, and H.I. Maibach Factors Affecting Children's Susceptibility to Chemicals, A. Makri, Michelle G. Goveia, and Rebecca Parkin Utilization of Irritation Data in Local Lymph node Assay, P. Ulrich and H.-W. Vohr Air Bag Injuries, M. Corazza, M. Rosaria Zampino, and A. Virgili Cigarette Smoking and Skin, Y.H. Leow Chemical Analysis of Tattoo Pigments Cleaved by Laser Light, R. Vasold Dermatotoxicology of Specialized Epithelia: Adapting Cutaneous Test Methods to Assess Topical Effects on the Vulva, M.A. Farage and H.I Maibach Anti-Irritant: Myth or Reality? An Overview, C. Ford and H.I. Maibach Evaluating Mechanical and Chemical Irritation Using the Behind-the-Knee Test: A Review, M.A. Farage The Need for More Sensitive Tools as We Reach the Limits of Our Ability to Detect Differences in Skin Effects from Mild Products, M.A. Farage Drug patch Testing in Systemic Cutaneous Drug Allergy, A. Barbaud Medical Device Regulation: An Introduction for the Practicing Physician, W.H. Maisel Diagnosis of Drug Hypersensitivity In Vitro, H. Merk and D.H. Obrigkeit Immunologic Patterns in Allergic and Irritant Contact Dermatitis: Similarities, E. Dika, N. Branco, and Howard I. Maibach Water Decontamination of Chemical Skin/Eye Splashes: A Critical Review, A.H. Hall and H.I. Maibach, Chemical Substances and Contact Allergy - 244 Substances According to Allergic Potency, E. Schlede, W. Aberer, T. Fuchs, I. Gerner, H. Lessmann T. Maurer, R. Rossbacher, G. Stropp, E. Wagner, and D. Kayser The Use of the Modified Forearm Controlled Application Test to Evaluate Skin Irritation of Lotion Formulations, M. Farage Hair in Toxicology, K.-i. O'gosh, Popliteal Lymph Node Assay, G. Ravel and J. Descotes Pigmentation Changes as a Result of Arsenic Exposure, N. Matveev and M.y Kile Textiles and Human Skin, Microclimate, Cutaneous Reactions: An Overview, W. Zhong, M.M.Q. Xing, N. Pan, and H.I. Maibach In Vivo Human Transfer of Topical Bioactive Drug between Individuals: Estradiol, R.C. Wester, X. Hui, and H.I. Maibach Is There Evidence that Geraniol Causes Allergic Contact Dermatitis? J.J. Hostnek and H.I. Maibach Operational Definition of a Causative Contact Allergen - A Study with Six Fragrance Allergens, J.J. Hostnek and H.I. Maibach Sodium Lauryl Sulfate-Induced Irritation in the Human Face: Regional and Age-Related Differences, S. Marrakchi and H.I. Maibach Ten Genotypes of Irritant Contact Dermatitis, A.-L. Chew and H.I. Maibach In vitro Skin Irritation Testing on SkinEthic(t) Reconstituted Human Epidermis: Reproducibility for 50 Chemicals Tested with Two Protocols, C. Tornier, M. Rosdy, and H.I. Maibach Identifying the source of textile-dye allergic contact dermatitis - A guideline, K.L. Hatch, H. Motschi, and H.I. Maibach Functional Map and Age Related Differences in the Human Face: Nonimmunologic Contact Urticaria Induced by Hexyl Nicotinate, S. Marrakchi and H.I. Maibach Is Contact Allergy in Man Life Long? An Overview of Patch Test Follow-Ups, E. Lee and H.I. Maibach Irritants in Combination with a Synergistic or Additive Effect on the Skin Response: An Overview of Tandem Irritation Studies, F. Kartono and H.I. Maibach Allergic Contact Dermatitis from Iodine Preparations: A Conundrum? S.K. Lee, H. Zhai, and H.I. Maibach Human Skin Buffering Capacity: An Overview, J. Levin, F. Dreher, and H.I. Maibach Appendix

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