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Author:   Yanlin Wang-Fischer (Palatin Technologies, Cranbury, New Jersey, USA)
Publisher:   Taylor & Francis Ltd
Imprint:   CRC Press
Weight:   0.453kg
ISBN:  

9781138409897

ISBN 10:   1138409898
Pages:   358
Publication Date:   12 October 2017
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Preface, About the Editor, Contributors, Chapter 1 Statistical Update of Stroke in America, Chapter 2 Rationale for Using Ischemic Stroke Models, Chapter 3 Animal Models of Ischemic Stroke: A Historical Survey, Chapter 4 Anatomy and Cerebral Circulation of the Rat, Chapter 5 Which Animal to Choose?, Chapter 6 Which Model to Use?, Chapter 7 Failure Is the Mother of Success: Why Neuroprotective Therapies That Work in Laboratories Fail in Clinical Trials, Chapter 8 Anesthesia of Laboratory Rats, Chapter 9 General Principles of Microsurgery on Animals, Chapter 10 Microsurgical Instruments for Stroke Studies, Chapter 11 Postoperative Care, Chapter 12 Surgery Procedure for Distal Middle Cerebral Artery Occlusion Model, Chapter 13 Surgical Models of Stroke Induced by Intraluminal Filament Implantation, Chapter 14 Embolic Stroke Models, Chapter 15 Photochemically Based Models of Focal Experimental Thrombotic Stroke in Rodents, Chapter 16 Induction of Asphyxia Cardiac Arrest in a Rat as a Model of Global Cerebral Ischemia, Chapter 17 Four-Vessel Occlusion Stroke Model in Rats, Chapter 18 Brain Hemorrhage Models in Rodents, Chapter 19 Endpoints for Stroke Studies, Chapter 20 Tissue Staining Techniques for Stroke Studies, Chapter 21 Protocol for Brain Vessel Corrosion Casting and Embedding, Chapter 22 Magnetic Resonance Imaging in Stroke Study, Chapter 23 Administration of Substances and Sampling, Chapter 24 Study Design in Animal Models of Stroke, Chapter 25 Common Biochemical and Physiological Parameters in Rats, Index

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Author Information

Yanlin Wang-Fischer, M.D., Ph.D., is a neuropharmacologist. She has worked in the pharmaceutical industry and academic environment for many years. Dr. Wang-Fischer earned her bachelor’s degree and doctor of medicine at Hunan Medical University, Changsha, China. Following clinical fellowship training in cardiovascular and metabolic diseases at Hunan Medical University, where she became an attending physician, she earned her Ph.D. in 1994. She completed her postdoctoral fellowship training at the School of Medicine at Laval University and at Boston University. Dr. Wang-Fischer joined the Howard Hughes Medical Institute at Yale University, New Haven, Connecticut, in 2000. She has contributed to several projects related to animal models and surgeries and produced an instructional video on studies of animals in vivo for new trainees. In 2002, Dr. Wang-Fischer joined the team of neurological disorders at Johnson & Johnson PRD, Raritan, New Jersey. She led projects based on different animal models to discover new drugs for treatment of stroke and neurological diseases. In 2006, Dr. Wang-Fischer joined Palatin Technologies and oversees projects on nasal and cerebral drug delivery. She has developed a novel technique to quickly assess nasal tolerance. Dr. Wang-Fischer has published more than 40 scientific articles in prestigious medical journals. Her current interests include neurological, cardiovascular, metabolic, and inflammatory diseases, mainly concerned with physiology and pharmacology in vivo.

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