Overview

The book series Nanomaterials for the Life Sciences, provides an in-depth overview of all nanomaterial types and their uses in the life sciences. Each volume is dedicated to a specific material class and covers fundamentals, synthesis and characterization strategies, structure-property relationships and biomedical applications. The series brings nanomaterials to the Life Scientists and life science to the Materials Scientists so that synergies are seen and developed to the fullest. Written by international experts of various facets of this exciting field of research, the series is aimed at scientists of the following disciplines: biology, chemistry, materials science, physics, bioengineering, and medicine, together with cell biology, biomedical engineering, pharmaceutical chemistry, and toxicology, both in academia and fundamental research as well as in pharmaceutical companies. VOLUME 4 - Magnetic Nanomaterials This volume takes the reader on a tour showing how magnetic nanomaterials are used in the fields of diagnosis and therapy, as well as in tissue engineering and environmental applications.

Full Product Details

Author:   Challa S. S. R. Kumar (Louisiana State University, Baton Rouge, USA)
Publisher:   Wiley-VCH Verlag GmbH
Imprint:   Blackwell Verlag GmbH
Dimensions:   Width: 17.00cm , Height: 3.80cm , Length: 24.10cm
Weight:   1.338kg
ISBN:  

9783527321544

ISBN 10:   3527321543
Pages:   672
Publication Date:   12 August 2009
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Out of stock  

Table of Contents

Preface PART I: Biosensing and Diagnosis NANOMATERIALS-BASED MAGNETIC RELAXATION SWITCH BIOSENSORS Introduction Superparamagnetic Nanoparticles Agglomeration-Based Sensing T2 Sensitivity of MRSW Particles Kinetics of Magnetic Relaxation Switch Biosensors Methods Development Micro-NMR of Magnetic Relaxation Switch Biosensors MULTIPLEXED DETECTION WITH MAGNETIC NANOPARTICLES Introduction Magnetism and Magnetic Particles Planar Arrays Rotating Discs Diagnostic Devices Bio-Barcode Assays Based on Magnetic Microspheres Spectrally Encoded Suspension Arrays of Magnetic Microspheres Magnetically Encoded Suspension Arrays Summary and Conclusions MAGNETOPHORETIC BIOSENSING AND SEPARATION USING MAGNETIC NANOMATERIALS Introduction Theory Magnetophoresis in Microfluidic Devices Magnetophoretic Biosensing Magnetophoretic Separation Concluding Remarks MAGNETIC NANOMATERIALS AS MRI CONTRAST AGENTS Introduction Classification of Magnetic Nanomaterials Used for MRI Applications Coating and Surface Functionalization of Magnetic Nanoparticles Properties and Characterization of Magnetic Nanoparticle Suspensions Application of Magnetic Nanomaterials in MRI Summary and Future Outlook PART II: Diagnosis and Therapy MAGNETIC NANOMATERIALS FOR IN VIVO AND IN VITRO CANCER DIAGNOSTICS Introduction Physico-Chemical Properties of Magnetic Nanoparticles Surface Coating for Improved Biocompatibility and Bioavailability MRI for In Vivo Diagnostics MRI for the Monitoring of Treatment Application of Magnetic Nanoparticles in In Vitro Diagnostics Detection of Circulating Tumor Cells Aptamers as an Alternative to Antibodies Conclusions MAGNETIC NANOPARTICLES FOR CANCER IMAGING AND THERAPY Introduction Synthesis and Surface Modifications of MNPs for Biological Applications Development of MNPs as Cancer Diagnosis and Imaging Agents MNPs Applied to Cancer Therapy Summary CORE-SHELL MAGNETIC NANOMATERIALS IN MEDICAL DIAGNOSIS AND THERAPY Introduction Synthesis Applications: Magnetic Resonance Imaging Applications: Hyperthermia and Thermal Ablation Application: Drug Delivery Summary and Perspectives PART III: Tissue Engineering THE USE OF MAGNETIC PARTICLES IN TISSUE ENGINEERING Introduction Magnetic Particle Technology Used in Various Tissue Types Summary and Concluding Remarks PART IV: Environmental Applications MAGNETIC NANOMATERIALS FOR ENVIRONMENTAL APPLICATIONS Introduction Synthesis and Functionalization of Magnetic Nanoparticles Magnetic Nanoparticles for the Separation and Detection of Analytes Summary and Future Perspective PART V: Biofunctionalization and Characterization MAGNETIC CORE-POLYMER SHELL NANOPARTICLES: SYNTHESIS AND BIOMEDICAL APPLICATIONS Introduction Synthesis of Magnetic Nanoparticles Magnetic Nanoparticles with Polymeric Shell Encapsulation of Magnetic Nanoparticles in a Polymeric Matrix Future Perspectives MAGNETOSOMES: BACTERIAL BIOSYNTHESIS OF MAGNETIC NANOPARTICLES AND POTENTIAL BIOMEDICAL APPLICATIONS Introduction Magnetic Nanoparticles for Medical Applications What Is Biomineralization? Biogenic Inorganic Materials Magnetosomes: Biomineraliization in Magnetic Bacteria Progress and Applications of Novel Biomedical Magnetosome Materials The Future for Biomedical Magnetosomes APPROACHES TO SYNTHESIS AND CHARACTERIZATION OF SPHERICAL AND ANISOMETRIC METALX OXIDE MAGNETIC NANOMATERIALS Introduction Magnetism in Nanostructured Metal Oxides Synthesis Methods for Spherical and Anisometric Iron Oxide Nanomaterials Correlations between Synthesis and Magnetic Behavior in Iron Oxide Nanomaterials Conclusions and Perspectives APPROACHES TO THE SYNTHESIS AND CHARACTERIZATION OF SPHERICAL AND ANISOTROPIC MAGNETIC ALLOY NANOMATERIALS Introduction Magnetic Noble Metal Alloy Nanoparticles Magnetic Early Transition Metal Alloy Nanoparticles Summary and Future Perspectives APPROACHES TO THE BIOFUNCTIONALIZATION OF SPHERICAL AND ANISOTROPIC IRON OXIDE NANOMATERIALS Introduction Magnetic Nanoparticle Synthesis Nanoparticle Functionalization Conclusions CHARACTERIZATION OF MAGNETIC NANOPARTICLES USING MAGNETIC FORCE MICROSCOPY Introduction Develoment of MFM Comparison of MFM to Other Techniques Physical Principles of MFM Noise in MFM MFM Cantilevers and Probes Probe Calibration Resolution in MFM MFM for Magnetic Nanoparticles The Application of MFM in the Life Sciences Limitations in MFM Recent Developments in MFM Summary and Future Perspectives COBALT NANOMATERIALS: SYNTHESIS AND CHARACTERIZATION Introduction The Characterization of Co Nanoparticles Synthesos of Cobalt-Based Nanoparticles Magnetic Properties of Co Nanoparticles Summary and Outlook

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Author Information

Challa Kumar is currently the Director of Nanofabrication & Nanomaterials at the Center for Advanced Microstructures and Devicees (CAMD), Baton Rouge, USA. He is also the President and CEO of Magnano Technologies, a company established to commercialize nanomaterials for applications in life sciences. His research interests are in developing novel synthetic methods, including those based on microfluidic reactors, for multifunctional nanomaterials. He has also been involved in the development of innovative therapeutic & diagnostic tools based on nanotechnology. He has eight years of industrial R&D experience working for Imperial Chemical Industries and United Breweries. He is the founding Editor-in-Chief of the Journal of Biomedical Nanotechnology, published by American Scientific Publishers and Series editor for the ten-volume book series, Nanotechnologies for the Life Sciences (NtLS), published by Wiley-VCH.

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