Overview

Magnetic nanomaterials (MNPs) have emerged as a significant advancement in nanotechnology, attracting considerable attention for their effective applications in the biomedical field. This book explores various methods of synthesis and characterization, as well as the diverse applications of MNPs, with a primary focus on cancer theranostics. Their superparamagnetic properties allow for precise control and enhance imaging techniques such as MRI, which facilitates high-resolution tumor detection and monitoring. In therapeutic settings, MNPs are utilized for magnetic hyperthermia, generating localized heat to selectively destroy cancer cells. Additionally, they function as nanocarriers for targeted drug delivery, ensuring the precise release of therapeutic agents at tumor sites while minimizing systemic toxicity. This book offers a comprehensive overview of recent clinical trials involving various MNPs in cancer theranostics, highlighting both ongoing clinical studies and approved applications. Key Features: Offers a holistic detailed approach in discussing magnetic nanoparticles in context of cancer treatment. Presents the latest research in this highly important field, with direct implication to cancer immunotherapeutics and precision cancer surgery. Incorporates critical research on the current and perceived toxicity of magnetic nanoparticles within human systems. Details actual ongoing clinical trials and those also proposed in the near future, as to the effects of magnetic nanomaterials to cancer treatment.

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Sudip Mukherjee, is an Assistant Professor at IIT (BHU), Varansi (India). He received his PhD in chemical sciences and nanomedicine at Calcutta University. From 2016 – 2020, he was a Postdoctoral Research Associate at Rice University in Houston TX. His primary research is in magnetic nanomaterials and associated fields, where he has published 56 referred journal articles and been awarded 6 patents, with two pending. He is a member of the Royal Society of Chemistry, Associate Editor, Fronters in Chemistry (Section: Nanoscience), Associate Editor, BMC Cancer, UK, member of the International Advisory Board, Materials Research Express, IOPScience, UK and a member of the American Chemical Society. He is an editorial referee for 8 different materials and nanomedicine journals. Vijay Sagar Madamsetty, received his PhD at the CSIR- Indian Institute of Chemical Technology and is currently employed as a Senior Scientist (Investigator) at CSL Seqirus Biopharmaceuticals, in Waltham MA (USA). Before that he was a postdoc for six years at the Mayo Clinic College of Medicine, where among other activities, he researched tumortargeted lipid nanoparticles which were established for effective delivery of CRISPr/RNA for pancreatic cancer treatment. Now his major work at CSL Seqoris deals with formulation support for preclinical studies and clinical trials, related the development of Lipid Nanoparticles, Magnetic Nanoparticlws and nRNA degradation mechanisms. He has published 29 accepted referred journal articles. Lipi Pradhan is a research scholar presently pursuing her Ph.D. degree in the School of Biomedical Engineering, IIT BHU, Varanasi. She has earned her M.Sc. in Zoology from the Department of Zoology, Ranchi University. Her research interest involved designing cell-based therapy for treating rare genetic disorders and green synthesis of nanoparticles for various biomedical applications. Devyani Yenurkar is a Prime Minister's Research Fellow (PMRF) in the School of Biomedical Engineering at the Indian Institute of Technology IIT(BHU). She received her master’s degree in pharmacy (Pharmaceutics) from SNDT University, Mumbai. Her present interest in research includes work with nanomaterials for their potential applications in the field of blood anticoagulation and thrombosis. Anjali Upadhyay is a research scholar pursuing her PhD from the School of Biomedical Engineering, IIT BHU, Varanasi. She did her master's (M.Sc.) from the University of Allahabad (Department of Zoology). Her research interests include inorganic biomaterials for antifibrotic, antibacterial, and antibiofilm applications.

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