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OverviewMagnetic fluid hyperthermia (MFH) uses magnetic nanoparticles (MNP) to transform the energy of an alternating magnetic field into heat via magnetic relaxation. This enables organ-confined cancer treatment by delivering cell-damaging temperatures higher than 43°C inside tumors. However, MNP-cell interaction restricts MNP mobility and causes MNP agglomeration, severely limiting the MNP heating behavior. Based on in vitro experiments, this book addresses the applicability of MFH to pancreatic tumor cells and discusses optimizations of intracellular MNP heating for clinical application. The impact of MNP-cell interaction on heating efficiency is quantified and compared to MNP systems mimicking intracellular conditions. Besides, Monte-Carlo simulation of MNP magnetic relaxation is used to predict optimal field parameters and MNP properties to maximize MFH efficiency under medical constraints. Full Product DetailsAuthor: Ulrich EngelmannPublisher: Infinite Science Publishing Imprint: Infinite Science Publishing Dimensions: Width: 17.00cm , Height: 1.60cm , Length: 24.40cm Weight: 0.485kg ISBN: 9783945954584ISBN 10: 3945954584 Pages: 302 Publication Date: 07 March 2019 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In stock  We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationDr. Ulrich Engelmann studied physics in Aachen (2007-2013) and conducted research at the 1st Institute of Physics IA and the Institute of Applied Medical Engineering in Aachen (2014-2018). His research activities span the mathematical modeling and biomedical application of nanoparticles for diagnostics and therapy. Tab Content 6Author Website:Countries AvailableAll regions |
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