Lynch Syndrome: Molecular Mechanism and Current Clinical Practice

Author:   Naohiro Tomita
Publisher:   Springer Verlag, Singapore
Edition:   1st ed. 2020
ISBN:  

9789811568930


Pages:   143
Publication Date:   26 August 2021
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Our Price $194.04 Quantity:  
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Lynch Syndrome: Molecular Mechanism and Current Clinical Practice


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Overview

This book offers a comprehensive review of Lynch Syndrome (LS), addressing both the basic and clinical aspects of this condition. Due to the recent advances in our understanding of the genetic mechanism of LS, and to new screening methods, including universal screening and/or multi-gene panel analysis, the standard treatment strategy for patients and family members of LS have been steadily improving. In this book, experts describe the disease’s manifestations, discuss state-of-the-art diagnosis and management options, and offer a cutting-edge overview of the genetic and epigenetic basis of the syndrome. Providing essential insights into this new phase in the management of LS, this book is a valuable resource not only for colorectal surgeons, but also for general gastrointestinal clinicians, gynecologists, oncologists and all basic researchers with an interest in LS.

Full Product Details

Author:   Naohiro Tomita
Publisher:   Springer Verlag, Singapore
Imprint:   Springer Verlag, Singapore
Edition:   1st ed. 2020
Weight:   0.304kg
ISBN:  

9789811568930


ISBN 10:   9811568936
Pages:   143
Publication Date:   26 August 2021
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1 Molecular mechanism of Lynch syndrome.- 2 Clinical features of Lynch syndrome.- 3 Pathology of Lynch syndrome-associated tumors.- 4 Immunohistochemistry for mismatch repair proteins.- 5 Genetic analysis for Lynch syndrome.- 6 Lynch syndrome-associated gynecological malignancies​.- 7 Lynch syndrome-associated urological malignancies.- 8 Screening for Lynch syndrome.- 9 Surveillance Colonoscopy for Lynch Syndrome Patients.- 10 Surgical approach for colorectal cancer in patients with Lynch syndrome.- 11 Immunotherapy for Lynch syndrome patients.- 12 Chemoprevention for Lynch syndrome-associated malignancies.- 13 International collaboration for Lynch syndrome.

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Author Information

Naohiro Tomita Professor Emeritus, Division of Lower GI Surgery, Department of Surgery, Hyogo College of Medicine Nishinomiya, Hyogo, Japan   Specially Appointed Adviser, Cancer Treatment Center, Toyonaka Municipal Hospital Toyonaka, Osaka, Japan ntomita@hyo-med.ac.jp  

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