Lymphocyte Development: Cell Selection Events and Signals During Immune Ontogeny
Author:   Shiv Pillai ,  D. Baltimore
Publisher:   Springer-Verlag New York Inc.
Edition:   Softcover Reprint of the Original 1st 2000 ed.
ISBN:  

9781461275398


Pages:   528
Publication Date:   07 October 2011
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Lymphocyte Development: Cell Selection Events and Signals During Immune Ontogeny


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Overview

""Lymphocyte Development"" presents an extremely up-to-date account of molecular processes involved in the development of lymphocytes. This well written book is based on a graduate course taught by the author. Topics include the selection processes involved in lymphocyte maturation, immune receptor gene rearrangement, signaling pathways involved in cell cycle progression and apoptosis, and the transcriptional regulation of lymphoid ontogeny. The book also covers T cell development and differentiation of helper and cytotoxic T cells as well as the development of Natural Killer lymphocytes. The book finishes with an account of the molecular basis of immunodeficiency syndromes. It will interest researchers in immunology and it will be useful as a supplementary text for a graduate level immunology course.

Full Product Details

Author:   Shiv Pillai ,  D. Baltimore
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   Softcover Reprint of the Original 1st 2000 ed.
Dimensions:   Width: 15.50cm , Height: 2.70cm , Length: 23.50cm
Weight:   0.814kg
ISBN:  

9781461275398


ISBN 10:   1461275393
Pages:   528
Publication Date:   07 October 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1 Overview of Cell Fate Decisions During Lymphoid Ontogeny.- 2 Commitment to a Lymphoid Fate.- 3 V(D)J Recombination and the Generation of Diversity.- 4 Pathways Mediating Signal Transduction and Cell Cycle Progression in Lymphocytes.- 5 Molecular Mechanisms of Lymphocyte Apoptosis.- 6 Lymphocyte Homing and the Generation of Secondary Lymphoid Organs.- 7 The Generation of Naive B Lymphocytes.- 8 Antigen-Induced B-Lymphocyte Differentiation.- 9 T Lymphocyte Development.- 10 The Activation and Differentiation of Mature T Lymphocytes.- 11 The Development of Natural Killer Cells.- 12 Naturally Occurring Disorders of Lymphocyte Development.

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