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9780128038093

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...a very comprehensive book that deals with the lung epithelial biology and molecular signaling involved in the normal lung and their implications in disease pathogenesis. It is very well written by experts in the field, highly illustrated, and presented in a very readable format. It is highly recommended for any clinician or scientist who is interested in the molecular and cellular workings of the lung. Score: 92 - 4 Stars --Doody's

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Dr. Sidhaye is an Associate Professor at Johns Hopkins University School of Medicine. Her laboratory is interested in studying lung epithelial cellular responses in chronic lung disease, with a focus on cytoskeleton and cell-cell adhesion. The long term goal is determining lung epithelial responses in COPD and identifying if these changes promote disease and whether we can identify targets to reverse disease. Dr. Koval's laboratory works on defining the molecular machinery that regulates formation of gap junctions (which coordinate intercellular signaling) and tight junctions (which promote tissue barrier function). The long term goal of his research is understanding how junctions are pathologically misregulated in lung injury and in diseases including alcoholic lung syndrome, acute respiratory distress syndrome and cystic fibrosis.

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