Overview
"In the thirty years since its discovery by Terje Lomo and Tim Bliss, Long Term Potentiation (LTP) has become one of the most extensively studied topics in contemporary neuroscience. In LTP the strength of synapses between neurons is potentiated following brief but intense activation. LTP is thought to play a central role in learning and memory, though the exact nature of its role is less clear. In spite of years of research, there are many questions about LTP regarding its functional relevance that remain unanswered - for example, is it a model of memory formation, or is the actual neural mechanism used by the brain to store information? This volume presents a state of the art account of LTP. It begins with lively accounts, by the scientists most closely involved, of the discovery of LTP and of the experiments that established its basic properties and induction mechanisms. Later contributions contain reviews and new research that cover the range of molecular, cellular, physiological and behavioural approaches to the study of LTP. Provocative, accessible, and authoritative, this book makes it clear why LTP continues in equal measure to puzzle and beguile neuroscientists today. Advance praise for Long Term Potentiation: ""This book provides a definitive overview of the development of ideas about synaptic plasticity and about the wide range of current research in this fascinating field."" Colin Blakemore, University of Oxford"
Full Product Details
Author: Timothy Bliss (, Division of Neurophysiology, National Institute for Medical Research, Mill Hill, London) ,
Graham Collingridge (, MRC Centre for Synaptic Plasticity, Department of Anatomy, University of Bristol) ,
Richard Morris (, Centre and Division of Neuroscience, University of Edinburgh)
Publisher: Oxford University Press
Imprint: Oxford University Press
Dimensions:
Width: 17.30cm
, Height: 2.90cm
, Length: 24.80cm
Weight: 0.889kg
ISBN: 9780198530305
ISBN 10: 0198530307
Pages: 420
Publication Date: 08 April 2004
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Hardback
Publisher's Status: Active
Availability: To order
Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us.
Reviews
from other books by this editor As a reference work for those working in any field related to EAA and NMDA receptors, this book is invaluable. Much of the history of the field of excitatory amino acids is contained within this book. I recommend it to the neuroscience researcher, as well as the clinician who wishes to have a reference work on the NMDA receptor on the bookshelf.
