Overview

A genetic defect in the synthesis and structure of collagen and connective tissue is the root cause of the more than ten distinct inherited, clinically and genetically diverse group of connective tissue disorders known as Ehlers-Danlos syndromes (EDS). 13 distinct variants of a new international classification were proposed in 2017. The skin, joints, and blood vessels can all be affected by Ehlers-Danlos syndrome. This syndrome is clinically diverse and classically classified into six types (classical, hypermobile, vascular, kyphoscoliotic, arthrochalasis, and dermatosparaxis), each of which has a distinct underlying collagen abnormality. The rare inherited conditions known as Ehlers-Danlos syndromes (EDS) affect connective tissue. Skin, tendons, ligaments, blood vessels, internal organs, and bones are all supported by connective tissues. There are a variety of EDS, some of which may share some symptoms. Some examples might be: Increased range of joint movement. joint hypermobility, Stretchy skin, or fragile skin that easily breaks or bruises. EDS can affect people in a variety of ways. The condition can be relatively mild for some people, while for others, its symptoms can be crippling. Faults in particular genes that weaken connective tissue are the root cause of the various forms of EDS. The defective gene may have been inherited from one parent or both, depending on the type of EDS. When a person is born with the defective gene, it may not be passed down from parent to child. Going through the pages of this manuscript, you would be enlightened on the possibilities of understanding and living healthy with the condition.

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