Liver Regeneration

Author:   Dieter Häussinger
Publisher:   De Gruyter
ISBN:  

9783110250787


Pages:   232
Publication Date:   27 May 2011
Format:   Hardback
Availability:   Awaiting stock   Availability explained
The supplier is currently out of stock of this item. It will be ordered for you and placed on backorder. Once it does come back in stock, we will ship it out for you.

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Liver Regeneration


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Overview

understanding the mechanisms involved in liver regeneration is of crucial importance for clinical medicine, not only regarding carcinogenesis and diabetes treatment, but also for the use of stem cells for cell therapy and liver surgery. This graduate-level text provides an overview of the current state of knowledge of the molecular mechanisms of liver regeneration. Hepatic stem cells are introduced and the important players involved in regeneration such as oval cells, bone marrow and stellate cells are reviewed. The cell signaling pathways that initiate liver regeneration and regulate the switch between proliferation and apoptosis are presented and the role of liver stem cells in tumorigenesis is discussed. The book also treats the epigenetic regulation of liver stem cells and the roles of inflammation and angiogenesis in liver regeneration. This compact overview of the fascinating regenerative capacity of the liver will be of interest to graduate students and post-docs in molecular biology, biochemistry and medicine.

Full Product Details

Author:   Dieter Häussinger
Publisher:   De Gruyter
Imprint:   De Gruyter
Weight:   0.404kg
ISBN:  

9783110250787


ISBN 10:   3110250780
Pages:   232
Publication Date:   27 May 2011
Audience:   Professional and scholarly ,  Professional & Vocational ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Awaiting stock   Availability explained
The supplier is currently out of stock of this item. It will be ordered for you and placed on backorder. Once it does come back in stock, we will ship it out for you.

Table of Contents

Liver regeneration: overview (Michalopoulos, USA) Oval cells, bone marrow and liver regeneration (B. Petersen, USA) Inflammation and liver regeneration (J. Bode) Liver stem cells and tumorigenesis (S. Thorgeirsson, USA) The hepatic stem cell niche (Sawitza) Stellate cells and liver regeneration (C. Kordes) Epigenetic regulation of stem cell factors during liver regeneration (Kordes) Hedgehog signalling and liver regeneration (Diehl, USA) The switch between proliferation and apoptosis in hepatic stellate cells (Reinehr) Angiogenesis and liver regeneration (Lammert)

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Author Information

Dieter Haussinger, Heinrich Heine University, Dusseldorf, Germany.

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