Lipoprotein(a)

Author:   Karam Kostner ,  Gerhard M. Kostner ,  Peter P. Toth
Publisher:   Springer International Publishing AG
Edition:   1st ed. 2023
ISBN:  

9783031245749


Pages:   443
Publication Date:   04 March 2023
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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Lipoprotein(a)


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Author:   Karam Kostner ,  Gerhard M. Kostner ,  Peter P. Toth
Publisher:   Springer International Publishing AG
Imprint:   Humana
Edition:   1st ed. 2023
Weight:   0.980kg
ISBN:  

9783031245749


ISBN 10:   3031245741
Pages:   443
Publication Date:   04 March 2023
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

60 years of Lp(a) research-From Ouchterlonys double diffusion to a significant risk factor for CHD.- Lp(a) structure and composition.- Genetics of Lipoprotein(a).- Lp(a) metabolism.- Contemporary aspects of Lp(a) metabolism and therapies based on tracer kinetic methods.- Role of Proprotein Convertase Subtilisin Kexin type 9 in Lipoprotein(a) Metabolism.- The Role of Cell Surface Receptors in Lp(a) Metabolism.- Physiological Roles And Functions Of Lipoprotein(a).- The role of Lp(a) in Atherosclerosis: An overview.- Role of macrophages in Lp(a) pathophysiology.- Thrombosis, Inflammation and Lipoprotein(a): Clinical Implications .- The role of the kidney in Lp(a) physiology and pathophysiology.- Lp(a) as a cardiovascular risk factor.- Lp(a) and aortic valve stenosis, stroke, and other non-coronary cardiovascular diseases.- Lp(a) in cardiovascular disease: Evidence from Large Epidemiological Studies.- Lipoprotein(A) And Immunity.- When to measure Lp(a) .- Measurement of Lipoprotein (a) in the Clinical Laboratory.- Standardization of analytical methods for the measurement of Lipoprotein(a): bridging  past and future initiatives.- Establishing an SI-traceable Reference Measurement System for Lp(a), based on Quantitative Protein Mass Spectrometry and Molar Units.- Compounds that impact Lp(a) concentrations.- Antisense oligonucleotide therapy to treat elevated lipoprotein(a).- Lipoprotein apheresis for reduction of Lipoprotein(a).- Elevated Lp(a) - Why Should I Test For It, If I Cannot Treat It? A Patient’s Perspective .- Burning unanswered questions Therapy.

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Author Information

Karam Kostner, MD, Ph.D., FRACP,  FCSANZ Associate Professor of Medicine University of Queensland and Mater Hospital Brisbane, Australia Gerhard M. Kostner, Ph.D. Emeritus Professor of Biochemistry and Molecular Biology Medical University of Graz, Austria Graz, Austria Peter P. Toth, M.D. , PhD, FAHA, FESC, FACC Adjunct Professor of Medicine Division of Cardiology Johns Hopkins University School of Medicine Baltimore, Maryland  USA

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