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OverviewParkinson's disease is the second most common neurodegenerative disease after Alzheimer. According to the United Nations, at least six million people are affected by PD worldwide. (2). Parkinson's disease occurs when certain neurons of the brain, mostly in the substantia nigra die or become impaired. The symptoms of Parkinson's disease result from the loss of these dopamine-secreting (dopaminergic) cells and subsequent loss of melanin, secreted by the same cells, in the pars compacta region of the substantia nigra (also known as black substance). This leads to inhibition of the direct pathway of movement and activation of the indirect pathway of movement. Since the direct pathway facilitates movement and the indirect pathway inhibits movement, the loss of these cells leads to a hypokinetic movement disorder. The lack of dopamine results in an excessive inhibition of the thalamus, leading to hypokinesia (3). Full Product DetailsAuthor: Y S MahindrakarPublisher: Independent Author Imprint: Independent Author Dimensions: Width: 15.20cm , Height: 1.00cm , Length: 22.90cm Weight: 0.249kg ISBN: 9780652227000ISBN 10: 0652227007 Pages: 180 Publication Date: 08 January 2023 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: Temporarily unavailable  The supplier advises that this item is temporarily unavailable. It will be ordered for you and placed on backorder. Once it does come back in stock, we will ship it out to you. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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