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Author:   John N. Abelson (California Institute of Technology, Division of Biology, Pasadena, U.S.A.) ,  Melvin I. Simon (The Salk Institute, La Jolla, CA, USA) ,  Byron Rubin (Lipomed, San Diego, California, U.S.A.) ,  Edward A. Dennis (University of California at San Diego, La Jolla, CA, U.S.A.)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Volume:   286
Dimensions:   Width: 15.20cm , Height: 3.30cm , Length: 22.90cm
Weight:   0.950kg
ISBN:  

9780121821876

ISBN 10:   0121821870
Pages:   563
Publication Date:   02 October 1997
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   In Print  
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

Table of Contents

"Regulation and Characterization: A.B.R. Thomson, A. De Pover, M. Keelan, E. Jarocka-Cyrta, and M.T. Clandinin, Inhibition of Lipid Absorption as an Approach to the Treatment of Obesity: An Overview. C. Holm, D. Langin, V. Manganiello, P. Belfrage, and E. Degerman, Regulation of Hormone-Sensitive Lipase Activity in Adipose Tissue. D.Y. Hui, Use of Gene Knockout Mice to Establish Lipase Function. R. Zolfaghari, R. Shamir, and E.A. Fisher, Properties of Pancreatic Carboxyl Ester Lipase in mRNA-Injected Xenopus Oocytes and Transfected Mammalian Hepatic and Intestinal Cells. G. Olivecrona and A. Lookene, Noncatalytic Functions of Lipoprotein Lipase. E.H. Harrison and E.S. Kempner, Radiation Inactivation Studies of Hepatic Cholesteryl Ester Hydrolases. M. Aoubala, I. Douchet, S. Bezzine, M. Hirn, R. Verger, and A. De Caro, Immunological Techniques for the Characterization of Digestive Lipases. Substrate and Inhibitor Characterization: D.M. Small, Physical Behavior of Lipase Substrates. T. Hongel, K. Jorgensen, D. Stokes, R.L. Biltonen, and O.G. Mouritsen, Phospholipase A2 Activity and Physical Properties of Lipid-Bilayer Substrates. S. Ransac, Y. Gargouri, F. Marguet, G. Buono, C. Beglinger, P. Hildebrand, H. Lengsfeld, P. Hadvary, and R. Verger, Covalent Inactivation of Lipases. S.R. Feaster and D.M Quinn, Mechanism-Based Inhibitors of Mammalian Cholesterol Esterase. L. Haalck and F. Spener, On the Inhibition of Microbial Lipases by Tetrahydrolipstatin. S. Ransac, M. Ivanova, R. Verger, and I. Panaiotov, Monolayer Techniques for Studying Lipase Kinetics. W.E. Momsen and H.L. Brockman, Recovery of Monomolecular Files in Studies of Lipolysis. S. Labourdenne, A. Cagna, B. Delorme, G. Esposito, R. Verger, and C. Riviere, Oil-Drop Tensiometer: Applications for Studying the Kinetics of Lipase Action. F. Ferrato, F. Carriere, L. Sarda, and R. Verger, A Critical Reevaluation of the Phenomenon of ""Interfacial Activation"". Biocatalytic Utility: U. Ader, P. Andersch, M. Berger, U. Goergens, B. Haase, J. Hermann, K. Laumen, R. Seemayer, C. Waldinger, and M.P. Schneider, Screening Techniques for Lipase Catalyst Selection. K. Hult and M. Holmquist, Kinetics, Molecular Modeling, and Synthetic Applications with Microbial Lipases. P. Andersch, M. Berger, J. Hermann, K. Laumen, M. Lobell, R. Seemayer, C. Waldinger, and M.P. Schneider, Ester Synthesis via AcylTransfer Transesterification. J.J. Lalonde, M.A. Navia, and A.L. Margolin, Cross-Linked Enzyme Crystals of Lipases as Catalysts for Kinetic Resolution of Acids and Alcohols. G.A. Hutcheon, P.J. Halling, and B.D. Moore, Measurement and Control of Hydration in Nonaqueous Biocatalysis. T. Anthonsen and J.A. Jongejan, Solvent Effect in Lipase-Catalyzed Racemate Resolution. E. Cernia and C. Palocci, Lipases in Supercritical Fluids. H. K.Weber and K. Faber, Stabilization of Lipases against Deactivation of Acetaldehyde Formed in Acyl Transfer Reactions. Author Index. Subject Index."

Reviews

Praise for the Series The Methods in Enzymology series represents the gold-standard. --NEUROSCIENCE Incomparably useful. --ANALYTICAL BIOCHEMISTRY It is a true 'methods' series, including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each page. --BIO/TECHNOLOGY The series has been following the growing, changing and creation of new areas of science. It should be on the shelves of all libraries in the world as a whole collection. --CHEMISTRY IN INDUSTRY The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced. --AMERICAN SOCIETY OF MICROBIOLOGY NEWS If we had some way to find the work most often consulted in the laboratory, it could well be the multi-volume series Methods in Enzymology...a great work. --ENZYMOLOGIA A series that has established itself as a definitive reference for biochemists. --JOURNAL OF CHROMATOGRAPHY

Author Information

Edward A. Dennis: University of California, San Diego Distinguished Professor of Chemistry and Biochemistry and former Department Chair and Professor of Pharmacology in the School of Medicine, Dennis is currently Editor-in-Chief of the Journal of Lipid Research and Director of the LIPID MAPS initiative. He also served as Chair of the Board of Directors of the Keystone Symposia on Molecular and Cellular Biology and current as an Emeritus member of the Board of Directors. His current research focus is on phospholipases, cell signaling and lipidomics on which he has published over 300 papers, most related to signal transduction by lipid messengers

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