Overview
LIFE - as a Matter of Fat
Lipidomics is the science of the fats called lipids. Lipids are as important for life as proteins, sugars, and genes. The present book presents a multi-disciplinary perspective on the physics of life and the particular role played by lipids and the lipid-bilayer component of cell membranes. The book is aimed at undergraduate students and young research workers within physics, chemistry, biochemistry, molecular biology, nutrition, as well as pharmaceutical and biomedical sciences. The emphasis is on the physical properties of lipid membranes seen as soft and molecularly structured interfaces. By combining and synthesizing insights obtained from a variety of recent studies, an attempt is made to clarify what membrane structure is and how it can be quantitatively described. Furthermore, it is shown how biological function mediated by membranes is controlled by lipid membrane structure and organization on length scales ranging from the size of the individual molecule, across molecular assemblies of proteins and lipid domains in the range of nanometers, to the size of whole cells. Applications of lipids in nano-technology and biomedicine are also described.
The Emerging Science of Lipidomics
We have just witnessed a scientific revolution at the end of the 20th century that took us through the genomics era with a focus on sequencing genes and mapping gene products. We are now in the middle of the proteomics era where the multitude of proteins that are encoded in the genes are identified and their functions are unveiled. In front of us we have a new era recognizing the role of lipids. The science of lipidomics is emerging. Lipidomics involves a quantitative experimental and theoretical study of, e.g. lipid and membrane self-assembly, lipid-protein interactions, lipid-gene interactions, and the biophysical properties of lipid structure, function, and dynamics.
Full Product Details
Author: Ole G Mouritsen
Publisher: Springer
Imprint: Springer
Dimensions:
Width: 23.40cm
, Height: 1.60cm
, Length: 15.60cm
Weight: 0.417kg
ISBN: 9783540804284
ISBN 10: 3540804285
Pages: 296
Publication Date: 04 September 2008
Audience:
General/trade
,
General
Format: Undefined
Publisher's Status: Unknown
Availability: Out of stock
Reviews
<p>From the reviews: <p> The book takes the reader on an exciting journey through the lipid world, and Mouritsen attracts the attention with a lively style of writing, and attitude to worldplay, as indicated in the book's title. (ChemBioChem 2005, 6, page 1463-1464)<p> This is a highly interesting book and a pleasure to read. It represents a new and excellent pedagogical introduction to the field of lipids and the biophysics of biological membranes. I reckon that physicists and chemists as well as biologists will benefit from this approach to the field and Mouritsen shows a deep insight into the physical chemistry of lipids. (G ran Lindblom, Chemistry and Physics of Lipids 2005, vol. 135, page 105-106)<p> This book is very much about many different aspects of the physical biochemistry of lipids. It covers the field in a very user friendly manner . Each chapter has a variety of useful diagrams and schematics illustrating the key points of the chapter. This book would make a useful con