Overview

The function of human white cells is dependent on a complex machinery involving a network of proteins. Their identification has posed a puzzle for scientists for many years and this book comprises the proceedings of the latest in a series of international meetings that have identified many of these entities and studied their function and clinical importance. Leucocyte Typing VII provides the definitive reference for all those working with antibodies recognising marker molecules on white blood cells. Sorting and tracing white blood cells is important in a range of clinical settings, but especially in the diagnosis of leukaemias. There is a concerted action by regulatory bodies looking for a standard against which these 'biologicals' can be assessed. The book contains the assembled work of many laboratories worldwide which jointly evaluated many hundered different monoclonal antibodies. The results of the collaborative effort reported at the meeting are published in Leucocyte Typing VII. A unique feature of this book is the complete guide to all available CD- antigens. This book is the standard reference for immunologists, cell and molecular biologists, haematologists, and pathologists working on white cell differentiation. It provides immunologists and biochemists with an up to date summary of the current knowledge of molecular aspects of different categories of human white cells (and endothelial and red cells) and provides hematologists and oncologists with information relevant to their clinical practice and research.

Full Product Details

Author:   David Mason (, Nuffield Department of Clinical Biochemistry and Cellular Science, John Radcliffe Hospital, Oxford) ,  Armand Bensussan ,  Chris Buckley ,  Curt Civin
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Dimensions:   Width: 23.00cm , Height: 4.90cm , Length: 28.50cm
Weight:   3.050kg
ISBN:  

9780192632524

ISBN 10:   0192632523
Pages:   1010
Publication Date:   04 April 2002
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   To order  
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Table of Contents

Part 1: Adhesion Structures Studies of existing CD molecules New CD antigens Miscellaneous studies Part 2: Apoptosis and Cell Fate Part 3: B Cells Studies of existing CD molecules New CD antigens Miscellaneous studies Part 4: Carbohydrates and Lectins Blind panel studies Studies of existing CD molecules New CD antigens Miscellaneous studies Part 5: Clinical Aspects of Leucocyte Molecules Part 6: Cytokine/Chemokine Receptors New CD antigens Miscellaneous studies Part 7: Dendritic Cells New CD antigens Miscellaneous studies Part 8: Endothelial Cells Studies of existing CD molecules New CD antigens Miscellaneous studies Part 9: Myeloid Cells Studies of existing CD Molecules New CD antigens Miscellaneous studies Part 10: New Technologies Part 11: Natural Killer Cells New CD antigens Miscellaneous stuides Part 12: Non-lineage Antigens Blind panel studies Studies of existing CD molecules New CD antigens Miscellaneous studies Part 13: Platelets Blind panel studies Studies of existing CD molecules New CD antigens Part 14: Red Cells New CD antigens Miscellaneous Studies Part 15: Stem/Progenitor Cells Studies of existing molecules New CD antigens Miscellaneous studies Part 16: Structural/Functional Asepects of Leucocyte Molecules Part 17: T Cells New CD antigens Miscellaneous Studies

Reviews

This book is extremely well presented, complete and easy to review, as the description of each CD molecule is short and substantiated by several good references. I can therefore recommend this book to both immunologists and haematologists working in the field, who are trying to understand the complexity of the CD system. Leukemia Journal

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