Overview

The third international workshop on leucocyte typing antigens brought together scientists from the major laboratories working in this complex and fast-moving field. In preparing for the workshop, more than 800 antibodies were exchanged. The results of these collaborative experiments were reported at the meeting, compared and summarized to produce a careful description of fifty human leucocyte antigens, twenty-four of them fully characterized for the first time. This book, contains the first and only complete account of these experiments and analyses. Antigens specific for or shared by T cells, activated lymphocytes, myeloid cells and platelets are featured. Details are given of their distribution, molecular structure and function. Much attention is given to the role that these antigens may play in investigating and understanding pathological processes, particularly in leukaemias and lymphomas. This workshop continues the collaboration established by A. Bernard and L. Boumsell, who organized the first workshop in 1980 (exchanging two hundred antibodies) bringing order and a standardized nomenclature to the field. Readership: immunologists, cell biologists, molecular biologists, haematologists and pathologists.

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9780192615527

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