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Author:   Frank Kozielski, FSB
Publisher:   Springer
Imprint:   Springer
Edition:   2015 ed.
Dimensions:   Width: 15.50cm , Height: 1.80cm , Length: 23.50cm
Weight:   6.017kg
ISBN:  

9789401797313

ISBN 10:   9401797315
Pages:   271
Publication Date:   24 March 2015
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Preface.- The kinesin superfamily.- The discovery and development of Eg5 inhibitors for the clinic.- Mechanism of action of Eg5 inhibitors.- Clinical trials of mitotic kinesin inhibitors.- Kif15; a useful target for anti-cancer therapy?.- Down-regulating CENP-E activity: for better or for worse.- The human kinesin-14 motor KifC1/HSET is an attractive anti-cancer drug target.-Kinesin-13 Microtubule Depolymerizing Proteins as targets for cancer therapy.- Chromokinesins in genome maintenance and cancer.- Kif14: a clinically relevant kinesin and potential target for cancer therapy.- Kinesin-8 members and their potential as biomarker or therapeutic target.- The kinesin-6 members MKLP1, MKLP2 and MPP.- Non-motor spindle proteins as cancer chemotherapy targets.- Inhibitors of mitotic kinesins for cancer treatment: consequences for neurons.- Index.

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