Overview

This broadly-based reference covers all aspects of both the normal and pathological degradation of the cartilage matrix - from basic descriptions of cartilage structure to potential treatments that promote repair or regeneration of damaged cartilage. Focusing on cartilage of the articular surfaces, this book presents all of the relevant biochemical background material; discusses in detail the building blocks of cartilage, such as collagen, aggrecan, glycoproteins and proteinases; considers both the biochemical and mechanical characteristics of cartilage breakdown; analyzes the whole organism, tissue culture and cell culture; and reviews regulatory factors, including hormones, growth factors, interleukins and retinoids.

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9780824787684

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. . .provides an excellent review of basic research in joint cartilage degradation, including in vivo and in vitro research. ---The Journal of Orthopedic and Sports Physical Therapy

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