Overview

This new edition of Introduction to the Cellular and Molecular Biology of Cancer provides a comprehensive overview of cancer biology, covering the current status of both research and treatment. For the student or new researcher the breadth of cancer research can appear daunting, yet a broad understanding is essential for translation of laboratory findings into the clinic. Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field, and the accompanying bibliographies allow rapid access to the relevant current literature. The book covers topics extending from the molecular alterations found in cancer cells and their causes to the current range of approaches to treatment. Since the publication of the previous edition in 1997 there has been unprecedented progress in cancer research: this is reflected by an extensive revision of all the material, and the addition of eight new chapters, covering DNA repair, epigenetic events, the cell cycle, cell immortalisation, apoptosis, angiogenesis, animal models, the genome, transcriptome and proteome, radiotherapy and molecular radiotherapy, immunotherapy, and gene therapy. The fourth edition of this popular book will serve as a text for both undergraduate and postgraduate use and also as an introduction for clinicians and scientists new to the field.

Full Product Details

Author:   Margaret Knowles (, Cancer Research UK Clinical Centre, Leeds, UK) ,  Peter Selby (, National Cancer Research Network, Leeds, UK)
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Edition:   4th Revised edition
Dimensions:   Width: 18.90cm , Height: 2.90cm , Length: 24.60cm
Weight:   1.215kg
ISBN:  

9780198525639

ISBN 10:   019852563
Pages:   549
Publication Date:   28 July 2005
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   To order  
Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us.

Table of Contents

1: L.M. Franks and Margaret A. Knowles: What is cancer? 2: Naomi Allen, Robert Newton, Amy Berrington de Gonzalez, Jane Green, Emily Banks, and Timothy J. Key: The causes of cancer 3: D. Timothy Bishop: Inherited susceptibility to cancer 4: Beate Köberle, John P. Wittschieben, and Richard D. Wood: DNA repair and cancer 5: Jonathan C. Cheng and Peter A. Jones: Epigenetic events in cancer 6: Denise Sheer and Janet Shipley: Molecular cytogenetics of cancer 7: Margaret A. Knowles: Oncogenes 8: Sonia Lain and David P. Lane: Tumour suppressor genes 9: Chris J. Norbury: The cancer cell cycle 10: Robert F. Newbold: Cellular immortalization and telomerase activation in cancer 11: Sally A. Prigent: Growth factors and their signalling pathways in cancer 12: Dean A. Fennell: Apoptosis: molecular physiology and significance for cancer therapeutics 13: Paul Farrell: Mechanisms of viral carcinogenesis 14: Peter W. Szlosarek and Frances R. Balkwill: Cytokines and cancer 15: Charlotte L. Bevan: Hormones and cancer 16: Ian Hart: The spread of tumours 17: K.Tahtis and R.Bicknell: Angiogenesis 18: Mel Greaves: Stem cells, heamopoiesis, and leukaemia 19: Jos Jonkers and Anton Berns: Animal models of cancer 20: Peter C. L. Beverley: The immunology of cancer 21: Tatjana Crnogorac-Jurcevic, Richard Poulsom, and Nicholas R. Lemoine: The molecular pathology of cancer 22: Silvana Debernardi, Rachel Craven, Bryan D. Young, and Rosamonde E. Banks: From transcriptome to proteome 23: Ian S. Fentiman: Local treatment of cancer 24: D.R. Camidge and D.I. Jodrell: Chemotherapy 25: Anne Kiltie: Radiotherapy and molecular radiotherapy 26: T. Geldart, M.J. Glennie, and P.W.M. Johnson: Monoclonal antibodies and therapy 27: Andrew M. Jackson and Joanne Porte: Immunotherapy of cancer 28: John David Chester: Cancer gene therapy 29: Peter Sasieni and Jack Cuzick: Screening 30: Peter Selby and Margaret A Knowles: Conclusions and prospects

Reviews

This book will be much appreciated by newcomers to cancer biology and will provide a concise and thought-provoking review for experts in the field. --Quarterly Review of Biology<br>

<br> This book will be much appreciated by newcomers to cancer biology and will provide a concise and thought-provoking review for experts in the field. --Quarterly Review of Biology<p><br>

Author Information

Margaret Knowles is Professor of Experimental Cancer Research at the University of Leeds, and Associate Director of the Cancer Research UK Clinical Centre, also in Leeds. Peter Selby is Professor of Cancer Medicine and Director of the National Cancer Research Network at the University of Leeds.

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