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Author:   Sangdun Choi
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   Softcover reprint of hardcover 1st ed. 2007
Dimensions:   Width: 17.80cm , Height: 2.80cm , Length: 25.40cm
Weight:   1.053kg
ISBN:  

9781617377297

ISBN 10:   1617377295
Pages:   542
Publication Date:   10 December 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Out of print, replaced by POD  
We will order this item for you from a manufatured on demand supplier.

Table of Contents

Scientific Challenges in Systems Biology.- Bringing Genomes to Life: The Use of Genome-Scale In Silico Models.- From Gene Expression to Metabolic Fluxes.- Experimental Techniques for Systems Biology.- Handling and Interpreting Gene Groups.- The Dynamic Transcriptome of Mice.- Dissecting Transcriptional Control Networks.- Reconstruction and Structural Analysis of Metabolic and Regulatory Networks.- Cross-Species Comparison Using Expression Data.- Methods for Protein-Protein Interaction Analysis.- Genome-Scale Assessment of Phenotypic Changes During Adaptive Evolution.- Location Proteomics.- Theoretical and Modeling Techniques.- Reconstructing Transcriptional Networks Using Gene Expression Profiling and Bayesian State-Space Models.- Modeling Spatiotemporal Dynamics of Multicellular Signaling.- Kinetics of Dimension-Restricted Conditions.- Mechanisms Generating Ultrasensitivity, Bistability, and Oscillations in Signal Transduction.- Employing Systems Biology to Quantify Receptor Tyrosine Kinase Signaling in Time and Space.- Dynamic Instabilities Within Living Neutrophils.- Efficiency, Robustness, and Stochasticity of Gene Regulatory Networks in Systems Biology: ? Switch as a Working Example.- Applications, Representation, and Management of Signaling Pathway Information: Introduction to the SigPath Project.- Methods and Software Platforms for Systems Biology.- SBML Models and MathSBML.- CellDesigner: A Graphical Biological Network Editor and Workbench Interfacing Simulator.- DBRF-MEGN Method: An Algorithm for Inferring Gene Regulatory Networks from Large-Scale Gene Expression Profiles.- Systematic Determination of Biological Network Topology: Nonintegral Connectivity Method (NICM).- Storing, Searching, and Disseminating Experimental Proteomics Data.- Representing andAnalyzing Biochemical Networks Using BioMaze.

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