Overview
This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis. • Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects • Provides examples of nonlinear modeling concepts and estimation basics with discussion on the model building process and applications of empirical Bayesian estimates in the drug development environment • Includes detailed chapters on data set structure, developing control streams for modeling and simulation, model applications, interpretation of NONMEM output and results, and quality control • Has datasets, programming code, and practice exercises with solutions, available on a supplementary website
Full Product Details
Author: Joel S. Owen ,
Jill Fiedler-Kelly
Publisher: John Wiley & Sons Inc
Imprint: John Wiley & Sons Inc
Dimensions:
Width: 15.50cm
, Height: 2.30cm
, Length: 23.60cm
Weight: 0.567kg
ISBN: 9780470582299
ISBN 10: 0470582294
Pages: 320
Publication Date: 29 July 2014
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Hardback
Publisher's Status: Active
Availability: Out of stock
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.
Reviews
This book may make the User Guide V experience a story from the good old times for the next generation of pharmacometricians. (CPT: Pharmacometrics & Systems Pharmacology, 22 December 2014)
<p> This book may make the User Guide V experience a story from the good old times for the next generation of pharmacometricians. (CPT: Pharmacometrics & Systems Pharmacology, 22 December 2014)
This book may make the User Guide V experience a story from the good old times for the next generation of pharmacometricians. (CPT: Pharmacometrics & Systems Pharmacology, 22 December 2014)
Author Information
Joel S. Owen is Professor of Pharmaceutics at Union University, Jackson, Tennessee and President and Principal Scientist of Joel S. Owen, LLC. He has led workshops on NONMEM and PK/PD modeling concepts and applications and served as Director PK/PD at Cognigen Corporation in Buffalo, New York. He has published 16 articles in research publications. Jill Fiedler-Kelly is Vice President and Chief Scientific Officer of Cognigen Corporation and Adjunct Associate Professor of Pharmaceutical Sciences at the University at Buffalo. She has been teaching workshops and graduate courses on population modeling for over 10 years and has published more than 20 articles and book chapters on pharmacokinetics and pharmacodynamics.
